Oxidative stress during HIV infection: mechanisms and consequences

AV Ivanov, VT Valuev-Elliston… - Oxidative medicine …, 2016 - Wiley Online Library
It is generally acknowledged that reactive oxygen species (ROS) play crucial roles in a
variety of natural processes in cells. If increased to levels which cannot be neutralized by the …

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

SW Perry, JP Norman, J Barbieri, EB Brown… - …, 2011 - Taylor & Francis
Fluorescent probes for monitoring mitochondrial membrane potential are frequently used for
assessing mitochondrial function, particularly in the context of cell fate determination in …

Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis

A Borrajo, C Spuch, MA Penedo, JM Olivares… - Annals of …, 2021 - Taylor & Francis
The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …

Oncogenic effects of HIV-1 proteins, mechanisms behind

M Isaguliants, E Bayurova, D Avdoshina… - Cancers, 2021 - mdpi.com
Simple Summary People living with human immunodeficiency virus type 1 (HIV-1)(PLWH)
are at increased risk of developing cancer despite successful antiretroviral therapy (ART) …

Organic fluorescent probes for detecting mitochondrial membrane potential

X Li, Y Zhao, J Yin, W Lin - Coordination Chemistry Reviews, 2020 - Elsevier
Mitochondrial membrane potential (MMP), as a key indicator of mitochondrial function, can
reflect the cellular health status. The dysfunction of MMP, even the subtle unusual changes …

Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and “fine tuning” modulation

JF Chen, PK Sonsalla, F Pedata, A Melani… - Progress in …, 2007 - Elsevier
This review summarizes recent developments that have contributed to understand how
adenosine receptors, particularly A2A receptors, modulate brain injury in various animal …

Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice

S Fitting, BM Ignatowska-Jankowska, C Bull… - Biological …, 2013 - Elsevier
BACKGROUND: Human immunodeficiency virus (HIV) associated neurocognitive disorders
(HAND), including memory dysfunction, continue to be a major clinical manifestation of HIV …

Infectious diseases

H Li, N Terrando, HA Gelbard - Microglia: Physiology, Pathophysiology …, 2024 - Springer
Microglia, brain-resident innate immune cells, have been extensively studied in
neurodegenerative contexts like Alzheimer's disease. The Coronavirus disease 2019 …

Role of p53 in neurodegenerative diseases

JR Chang, M Ghafouri, R Mukerjee… - Neurodegenerative …, 2012 - karger.com
Background: p53 plays an important role in many areas of cellular physiology and biology,
ranging from cellular development and differentiation to cell cycle arrest and apoptosis …

[HTML][HTML] Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons

S Fitting, R Xu, C Bull, SK Buch, N El-Hage… - The American journal of …, 2010 - Elsevier
HIV-1 infection predisposes the central nervous system to damage by opportunistic
infections and environmental insults. Such maladaptive plasticity may underlie the …