Copy number variation in domestication

ZN Lye, MD Purugganan - Trends in Plant Science, 2019 - cell.com
Domesticated plants have long served as excellent models for studying evolution. Many
genes and mutations underlying important domestication traits have been identified, and …

Molecular tools and analytical approaches for the characterization of farm animal genetic diversity

JA Lenstra, LF Groeneveld, H Eding… - Animal …, 2012 - Wiley Online Library
Genetic studies of livestock populations focus on questions of domestication, within‐and
among‐breed diversity, breed history and adaptive variation. In this review, we describe the …

Copy number variation of individual cattle genomes using next-generation sequencing

DM Bickhart, Y Hou, SG Schroeder, C Alkan… - Genome …, 2012 - genome.cshlp.org
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Copy number variation in the genomes of domestic animals

A Clop, O Vidal, M Amills - Animal genetics, 2012 - Wiley Online Library
Copy number variation (CNV) might be one of the main contributors to phenotypic diversity
and evolutionary adaptation in animals and plants, employing a wide variety of mechanisms …

The challenges and importance of structural variation detection in livestock

DM Bickhart, GE Liu - Frontiers in genetics, 2014 - frontiersin.org
Recent studies in humans and other model organisms have demonstrated that structural
variants (SVs) comprise a substantial proportion of variation among individuals of each …

Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing

X Cui, Y Hou, S Yang, Y Xie, S Zhang, Y Zhang… - BMC genomics, 2014 - Springer
Abstract Background Recently, RNA sequencing (RNA-seq) has rapidly emerged as a major
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …

Bovine Exome Sequence Analysis and Targeted SNP Genotyping of Recessive Fertility Defects BH1, HH2, and HH3 Reveal a Putative Causative Mutation in SMC2 …

MC McClure, D Bickhart, D Null, P VanRaden, L Xu… - PloS one, 2014 - journals.plos.org
The recent discovery of bovine haplotypes with negative effects on fertility in the Brown
Swiss, Holstein, and Jersey breeds has allowed producers to identify carrier animals using …

A meta-assembly of selection signatures in cattle

IAS Randhawa, MS Khatkar, PC Thomson… - PloS one, 2016 - journals.plos.org
Since domestication, significant genetic improvement has been achieved for many traits of
commercial importance in cattle, including adaptation, appearance and production. In …

Genome-wide detection of CNVs in Chinese indigenous sheep with different types of tails using ovine high-density 600K SNP arrays

C Zhu, H Fan, Z Yuan, S Hu, X Ma, J Xuan, H Wang… - Scientific reports, 2016 - nature.com
Chinese indigenous sheep can be classified into three types based on tail morphology: fat-
tailed, fat-rumped, and thin-tailed sheep, of which the typical breeds are large-tailed Han …

Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins

L Jiang, J Jiang, J Yang, X Liu, J Wang, H Wang… - BMC genomics, 2013 - Springer
Abstract Background Copy number variations (CNVs) are widespread in the human or
animal genome and are a significant source of genetic variation, which has been …