The role of sinusoidal endothelial cells in the axis of inflammation and cancer within the liver
AL Wilkinson, M Qurashi, S Shetty - Frontiers in physiology, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …
Resolving the fibrotic niche of human liver cirrhosis at single-cell level
P Ramachandran, R Dobie, JR Wilson-Kanamori… - Nature, 2019 - nature.com
Liver cirrhosis is a major cause of death worldwide and is characterized by extensive
fibrosis. There are currently no effective antifibrotic therapies available. To obtain a better …
fibrosis. There are currently no effective antifibrotic therapies available. To obtain a better …
More than just a removal service: scavenger receptors in leukocyte trafficking
Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their
inherent ability to bind and internalize a wide array of structurally diverse ligands which can …
inherent ability to bind and internalize a wide array of structurally diverse ligands which can …
[HTML][HTML] Anionic 1, 2-distearoyl-sn-glycero-3-phosphoglycerol (DSPG) liposomes induce antigen-specific regulatory T cells and prevent atherosclerosis in mice
N Benne, J van Duijn, FL Vigario, RJT Leboux… - Journal of controlled …, 2018 - Elsevier
Atherosclerosis is the predominant underlying pathology of many types of cardiovascular
disease and is one of the leading causes of death worldwide. It is characterized by the …
disease and is one of the leading causes of death worldwide. It is characterized by the …
SCARF1: a multifaceted, yet largely understudied, scavenger receptor
DA Patten - Inflammation Research, 2018 - Springer
Background As is a prerequisite of belonging to the scavenger receptor super family,
SCARF1 (scavenger receptor class F, member 1) is known to play a key role in the binding …
SCARF1 (scavenger receptor class F, member 1) is known to play a key role in the binding …
The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration
AL Wilkinson, S Hulme, JI Kennedy, ER Mann, P Horn… - Iscience, 2023 - cell.com
Liver sinusoidal endothelial cells (LSEC) undergo significant phenotypic change in chronic
liver disease (CLD), and yet the factors that drive this process and the impact on their …
liver disease (CLD), and yet the factors that drive this process and the impact on their …
Scavenger receptors: novel roles in the pathogenesis of liver inflammation and cancer
DA Patten, AL Wilkinson, A O'Keeffe… - Seminars in Liver …, 2022 - thieme-connect.com
The scavenger receptor superfamily represents a highly diverse collection of evolutionarily-
conserved receptors which are known to play key roles in host homeostasis, the most …
conserved receptors which are known to play key roles in host homeostasis, the most …
Responsible Genes for Neuronal Migration in the Chromosome 17p13.3: Beyond Pafah1b1(Lis1), Crk and Ywhae(14-3-3ε)
X Liu, SA Bennison, L Robinson, K Toyo-Oka - Brain sciences, 2021 - mdpi.com
The 17p13. 3 chromosome region is often deleted or duplicated in humans, resulting in
severe neurodevelopmental disorders such as Miller–Dieker syndrome (MDS) and 17p13. 3 …
severe neurodevelopmental disorders such as Miller–Dieker syndrome (MDS) and 17p13. 3 …
Factors of Nasopharynx that Favor the Colonization and Persistence of Staphylococcus aureus
S González-García, A Hamdan-Partida… - Pharynx-Diagnosis …, 2021 - books.google.com
Between 30 and 50% of the world population is permanently colonized in some anatomical
site by Staphylococcus aureus, although the vast majority are asymptomatic carriers. The …
site by Staphylococcus aureus, although the vast majority are asymptomatic carriers. The …
SCARF1-induced efferocytosis plays an immunomodulatory role in humans, and autoantibodies targeting SCARF1 are produced in patients with systemic lupus …
Deficiency in the clearance of cellular debris is a major pathogenic factor in the emergence
of autoimmune diseases. We previously demonstrated that mice deficient for scavenger …
of autoimmune diseases. We previously demonstrated that mice deficient for scavenger …