[HTML][HTML] A comprehensive review on modeling aspects of infusion-based drug delivery in the brain
Brain disorders represent an ever-increasing health challenge worldwide. While
conventional drug therapies are less effective due to the presence of the blood-brain barrier …
conventional drug therapies are less effective due to the presence of the blood-brain barrier …
Mechanical properties of brain tissue based on microstructure
C Zhang, C Liu, H Zhao - Journal of the Mechanical Behavior of Biomedical …, 2022 - Elsevier
Research on the mechanical properties of brain tissue has gradually deepened recently.
Two indentation protocols were used here to characterize the mechanical properties of …
Two indentation protocols were used here to characterize the mechanical properties of …
Inverse identification of region-specific hyperelastic material parameters for human brain tissue
The identification of material parameters accurately describing the region-dependent
mechanical behavior of human brain tissue is crucial for computational models used to …
mechanical behavior of human brain tissue is crucial for computational models used to …
Long-term recovery behavior of brain tissue in hydrocephalus patients after shunting
S Gholampour, D Frim, B Yamini - Communications Biology, 2022 - nature.com
The unpredictable complexities in hydrocephalus shunt outcomes may be related to the
recovery behavior of brain tissue after shunting. The simulated cerebrospinal fluid (CSF) …
recovery behavior of brain tissue after shunting. The simulated cerebrospinal fluid (CSF) …
[HTML][HTML] Towards animal surrogates for characterising large strain dynamic mechanical properties of human brain tissue
The regional dynamic mechanical properties of mouse, rat, pig, and human brain tissue
were compared directly in this first-of-its-kind study. Our results suggest the use of pig or …
were compared directly in this first-of-its-kind study. Our results suggest the use of pig or …
[HTML][HTML] On the importance of using region-dependent material parameters for full-scale human brain simulations
An accurate finite element (FE) model of the human brain reliably predicting its response to
loading offers great possibilities for brain injury prevention, disease prediction, and surgical …
loading offers great possibilities for brain injury prevention, disease prediction, and surgical …
Toward a comprehensive delineation of white matter tract-related deformation
Finite element (FE) models of the human head are valuable instruments to explore the
mechanobiological pathway from external loading, localized brain response, and resultant …
mechanobiological pathway from external loading, localized brain response, and resultant …
Tissue‐scale biomechanical testing of brain tissue for the calibration of nonlinear material models
Brain tissue is one of the most complex and softest tissues in the human body. Due to its
ultrasoft and biphasic nature, it is difficult to control the deformation state during …
ultrasoft and biphasic nature, it is difficult to control the deformation state during …
[HTML][HTML] A finite element model of contusion spinal cord injury in rodents
R Frantsuzov, S Mondal, CM Walsh… - Journal of the …, 2023 - Elsevier
Traumatic spinal cord injuries result from high impact forces acting on the spine and are
proceeded by an extensive secondary inflammatory response resulting in motor, sensory …
proceeded by an extensive secondary inflammatory response resulting in motor, sensory …
Effects of Different Types of Electric Fields on Mechanical Properties and Microstructure of Ex Vivo Porcine Brain Tissues
C Zhang, Y Li, S Huang, L Yang… - ACS Biomaterials Science …, 2022 - ACS Publications
Electrotherapy plays a crucial role in regulating neuronal activity. Nevertheless, the relevant
therapeutic mechanisms are still unclear; thus, the effects of electric fields on brain tissue's …
therapeutic mechanisms are still unclear; thus, the effects of electric fields on brain tissue's …