Fixed dose drug combinations–are they pharmacoeconomically sound? Findings and implications especially for lower-and middle-income countries

B Godman, H McCabe, TD Leong… - Expert review of …, 2020 - Taylor & Francis
Introduction There are positive aspects regarding the prescribing of fixed dose combinations
(FDCs) versus prescribing the medicines separately. However, these have to be balanced …

Oral fixed-dose combination pharmaceutical products: Industrial manufacturing versus personalized 3D printing

R Fernández-García, M Prada… - Pharmaceutical …, 2020 - Springer
Fixed-dose combination (FDC) products containing at least two different active
pharmaceutical ingredients are designed to treat more effectively different pathologies as …

[HTML][HTML] Impact of single-pill combination therapy on adherence, blood pressure control, and clinical outcomes: a rapid evidence assessment of recent literature

K Tsioufis, R Kreutz, G Sykara, J van Vugt… - Journal of …, 2020 - journals.lww.com
Objective: The 2018 European Society of Cardiology/European Society of Hypertension
Guidelines for the management of arterial hypertension raised the need for evidence to …

Two‐drug fixed‐dose combinations of blood pressure‐lowering drugs as WHO essential medicines: an overview of efficacy, safety, and cost

A Salam, MD Huffman, R Kanukula… - The Journal of …, 2020 - Wiley Online Library
Cardiovascular diseases (CVD) are the world's leading cause of death. High blood pressure
(BP) is the leading global risk factor for all‐cause preventable morbidity and mortality …

Pharmaceutical application and development of fixed-dose combination: Dosage form review

DW Kim, KY Weon - Journal of Pharmaceutical Investigation, 2021 - Springer
Background Fixed dose combination (FDC) products are common in the treatment of various
disease such as hypertension, diabetes, HIV and HCV, Pain, Respiratory disease for …

Fixed-dose combination medications for treating hypertension: A review of effectiveness, safety, and challenges

J An, CG Derington, T Luong, KL Olson, JB King… - Current Hypertension …, 2020 - Springer
Abstract Purpose of Review To summarize the recent evidence on the effectiveness and
safety of antihypertensive fixed-dose combination (FDC) medications, and to describe the …

Ability of machine-learning based clinical decision support system to reduce alert fatigue, wrong-drug errors, and alert users about look alike, sound alike medication

CY Chen, YL Chen, J Scholl, HC Yang… - Computer Methods and …, 2024 - Elsevier
Background and objective The overall benefits of using clinical decision support systems
(CDSSs) can be restrained if physicians inadvertently ignore clinically useful alerts due to …

The feasibility of polypill for cardiovascular disease prevention in Asian Population

A Sukonthasarn, YC Chia, JG Wang… - The Journal of …, 2021 - Wiley Online Library
Polypill is a fixed‐dose combination of medications with proven benefits for the prevention of
cardiovascular disease (CVD). Its role in CVD prevention has been extensively debated …

Preoperative management of cardiovascular medications: a society for perioperative assessment and quality improvement (spaqi) consensus statement

SK Sahai, K Balonov, N Bentov, DMM Bierle… - Mayo Clinic …, 2022 - Elsevier
Cardiovascular conditions such as hypertension, arrhythmias, and heart failure are common
in patients undergoing anesthesia for surgical or other procedures. Numerous guidelines …

The use of single-pill combinations as first-line treatment for hypertension: translating guidelines into clinical practice

E Campana, V Cunha, S Glaveckaite… - Journal of …, 2020 - journals.lww.com
Abstract The 2008 European Society of Cardiology/European Society of Hypertension
guidelines recommend the first-line prescription of two antihypertensive drugs in single-pill …