A constant metabolism and energy supply are crucial to all organs, particularly the brain.
Age-dependent neurodegenerative diseases, such as Parkinson's disease (PD), are …

Nurr1, a transcription factor belonging to the orphan nuclear receptor superfamily, is critical
in the development and maintenance of the dopaminergic system and as such it may have …

The response of osteoprogenitors to calcium (Ca2+) is of primary interest for both normal
bone homeostasis and the clinical field of bone regeneration. The latter makes use of …

Nuclear receptors (NRs) regulate and coordinate multiple processes by integrating internal
and external signals, thereby maintaining homeostasis in front of nutritional, behavioral and …

Parathyroid hormone (PTH) increases FGF23 mRNA and protein levels in vivo and in vitro.
Here we tested whether the increased FGF23 expression by PTH is mediated by the orphan …

Nuclear receptor related 1 (Nurr1) is a transcription factor with neuroprotective and
antineuroinflammatory properties. Observations from genetic studies and human patients …

Dental pulp stem cells (DPSCs) are an adult stem cell population with high proliferative
potential and the ability to differentiate in many cell types, and this has led scientists to …

Many lines of research implicate cyclooxygenase 2-derived prostaglandins in tumor growth
and metastasis. More specifically, we have shown that prostaglandin E 2 (PGE 2) promotes …

The hormonal vitamin D metabolite, 1, 25‐dihydroxyvitamin D [1, 25 (OH) 2D], produced in
kidney, acts in numerous end organs via the nuclear vitamin D receptor (VDR) to trigger …

BACKGROUND: Medial arterial calcification is a chronic systemic vascular disorder distinct
from atherosclerosis and is commonly observed in patients with chronic kidney disease …