Diabetes Mellitus: insights from epidemiology, biochemistry, risk factors, diagnosis, complications and comprehensive management

S Alam, MK Hasan, S Neaz, N Hussain, MF Hossain… - Diabetology, 2021 - mdpi.com
Diabetes mellitus has become a serious and chronic metabolic disorder that results from a
complex interaction of genetic and environmental factors, principally characterized by …

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

AC Sedgwick, L Wu, HH Han, SD Bull, XP He… - Chemical Society …, 2018 - pubs.rsc.org
In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …

Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway

GH Chen, CC Song, K Pantopoulos, XL Wei… - Free Radical Biology …, 2022 - Elsevier
Ferroptosis is a regulated form of cell death induced by iron (Fe)-dependent lipid
peroxidation. At present, the underlying molecular mechanisms remain elusive. Herein, we …

The role of zinc, copper, manganese and iron in neurodegenerative diseases

L Mezzaroba, DF Alfieri, ANC Simão, EMV Reiche - Neurotoxicology, 2019 - Elsevier
Metals are involved in different pathophysiological mechanisms associated with
neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's …

A dual role of heme oxygenase-1 in cancer cells

SK Chiang, SE Chen, LC Chang - International journal of molecular …, 2018 - mdpi.com
Heme oxygenase (HO)-1 is known to metabolize heme into biliverdin/bilirubin, carbon
monoxide, and ferrous iron, and it has been suggested to demonstrate cytoprotective effects …

Iron metabolism: pathophysiology and pharmacology

K Roemhild, F von Maltzahn, R Weiskirchen… - Trends in …, 2021 - cell.com
Iron is essential in many physiological processes, including DNA metabolism, oxygen
transport, and cellular energy generation. Deregulated iron metabolism, which results in iron …

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

YN Zhang, W Poon, AJ Tavares, ID McGilvray… - Journal of controlled …, 2016 - Elsevier
99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue …

Iron homeostasis disorder and Alzheimer's disease

Y Peng, X Chang, M Lang - International journal of molecular sciences, 2021 - mdpi.com
Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

Overview of carbon nanotubes for biomedical applications

J Simon, E Flahaut, M Golzio - Materials, 2019 - mdpi.com
The unique combination of mechanical, optical and electrical properties offered by carbon
nanotubes has fostered research for their use in many kinds of applications, including the …

Prospects of artificial meat: Opportunities and challenges around consumer acceptance

L Zhang, Y Hu, IH Badar, X Xia, B Kong… - Trends in Food Science & …, 2021 - Elsevier
Background Artificial meat offers a potential solution to consumer demand for meat, given
global environmental concerns, public health problems, sustainability, and animal welfare …