Proteins from the DNA damage response: Regulation, dysfunction, and anticancer strategies
C Molinaro, A Martoriati, K Cailliau - Cancers, 2021 - mdpi.com
Simple Summary Cells respond to genotoxic stress through complex protein pathways
called DNA damage response (DDR). These mechanisms ensure the preservation of …
called DNA damage response (DDR). These mechanisms ensure the preservation of …
Genome instability in multiple myeloma: Facts and factors
Simple Summary Multiple myeloma is an incurable blood cancer caused by the malignant
transformation of immunoglobulin-producing plasma cells. The mechanisms leading to the …
transformation of immunoglobulin-producing plasma cells. The mechanisms leading to the …
Functionalized nanomaterials-based electrochemiluminescent biosensors and their application in cancer biomarkers detection
To detect a range of trace biomarkers associated with human diseases, researchers have
been focusing on developing biosensors that possess high sensitivity and specificity …
been focusing on developing biosensors that possess high sensitivity and specificity …
Circulating tumour cells, cell free DNA and tumour-educated platelets as reliable prognostic and management biomarkers for the liquid biopsy in multiple myeloma
Simple Summary Even though the presently employed biomarkers in the detection and
management of multiple myeloma are demonstrating encouraging results, the mortality …
management of multiple myeloma are demonstrating encouraging results, the mortality …
[HTML][HTML] Liquid biopsy: an evolving paradigm for the biological characterisation of plasma cell disorders
Liquid biopsies—a source of circulating cell-free nucleic acids, proteins and extracellular
vesicles—are currently being explored for the quantitative and qualitative characterisation of …
vesicles—are currently being explored for the quantitative and qualitative characterisation of …
Electrochemiluminescent/Electrochemical ratiometric biosensor for extremely specific and ultrasensitive detection of circulating tumor DNA
L Yang, X Zhou, K Zhang, J Liu, L Zhao, A Cai… - Sensors and Actuators B …, 2023 - Elsevier
Abstract Herein, an electrochemiluminescent (ECL)/electrochemical (EC) ratiometric
biosensor was developed for the ultrasensitive determination of circulating tumor DNA …
biosensor was developed for the ultrasensitive determination of circulating tumor DNA …
Circulating tumour DNA analysis predicts relapse and improves risk stratification in primary refractory multiple myeloma
Dear Editor, Multiple myeloma (MM), an incurable plasma cell malignancy, is the second
most common form of blood cancer with a 5-year overall survival (OS) of 48.5% for newly …
most common form of blood cancer with a 5-year overall survival (OS) of 48.5% for newly …
Human myeloma cell‐and plasma‐derived extracellular vesicles contribute to functional regulation of stromal cells
Circulating small extracellular vesicles (sEV) represent promising non‐invasive biomarkers
that may aid in the diagnosis and risk‐stratification of multiple myeloma (MM), an incurable …
that may aid in the diagnosis and risk‐stratification of multiple myeloma (MM), an incurable …
Clinical significance of circulating cell-free DNA detection in multiple myeloma: a meta-analysis
X Ye, W Li, L Zhang, J Yu - Frontiers in Oncology, 2022 - frontiersin.org
Circulating cell-free DNA (cfDNA) detection, a non-invasive method, appears promising for
genetic analyses as well as quantitative assessment of tumor burden in patients with cancer …
genetic analyses as well as quantitative assessment of tumor burden in patients with cancer …
Measurable residual disease in peripheral blood in myeloma: dream or reality
Measurable residual disease in peripheral blood in myeloma:... : Current Opinion in Oncology
Measurable residual disease in peripheral blood in myeloma: dream or reality : Current Opinion …
Measurable residual disease in peripheral blood in myeloma: dream or reality : Current Opinion …