Recent developments in solvent-free multicomponent reactions: a perfect synergy for eco-compatible organic synthesis

MS Singh, S Chowdhury - Rsc Advances, 2012 - pubs.rsc.org
Multicomponent reactions have gained significant importance as a tool for the synthesis of a
wide variety of useful compounds, including pharmaceuticals. In this context, the multiple …

Biginelli reaction mediated synthesis of antimicrobial pyrimidine derivatives and their therapeutic properties

M Marinescu - Molecules, 2021 - mdpi.com
Antimicrobial resistance was one of the top priorities for global public health before the start
of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical …

Brønsted Base-Catalyzed One-Pot Three-Component Biginelli-Type Reaction: An Efficient Synthesis of 4,5,6-Triaryl-3,4-dihydropyrimidin-2(1H)-one and Mechanistic …

ZL Shen, XP Xu, SJ Ji - The Journal of Organic Chemistry, 2010 - ACS Publications
An efficient one-pot synthesis of 4, 5, 6-triaryl-3, 4-dihydropyrimidin-2 (1 H)-ones via a three-
component Biginelli-type condensation of aldehyde, 2-phenylacetophenone, and …

Past, present and future of the Biginelli reaction: a critical perspective.

JS Sandhu - ARKIVOC: Online Journal of Organic …, 2012 - search.ebscohost.com
This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

A chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis

MA Kolosov, VD Orlov, DA Beloborodov… - Molecular diversity, 2009 - Springer
Despite prior reports of several really effective catalytic and non-catalytic approaches
towards Biginelli's 3, 4-dihydropyrimidin-2 (1 H)-ones, an overwhelming number of new …

Sulfanilic acid-functionalized silica-coated magnetite nanoparticles as an efficient, reusable and magnetically separable catalyst for the solvent-free synthesis of 1 …

H Moghanian, A Mobinikhaledi, AG Blackman… - RSC …, 2014 - pubs.rsc.org
Sulfanilic acid-functionalized silica-coated nano-Fe3O4 particles (MNPs–PhSO3H) have
been prepared as a reusable heterogeneous acid catalyst using a facile process. The …

Niobium oxides as heterogeneous catalysts for Biginelli multicomponent reaction

LG do Nascimento, IM Dias… - The Journal of …, 2020 - ACS Publications
This study reports a simple, reusable, and recoverable niobium-based heterogeneous
catalysts for Biginelli multicomponent reactions. Different methods of catalysts preparation …

[HTML][HTML] An improved eco-friendly and solvent-free method for the one-pot synthesis of tetrahydropyrimidine derivatives via Biginelli condensation reaction using ZrO2 …

G Balraj, K Rammohan, MS Babu, D Ayodhya - Results in Chemistry, 2023 - Elsevier
The objective of the present study is focused on the facile synthesis of ZrO 2/La 2 O 3
catalyst and the catalytic performance was evaluated towards one-pot synthesis of …

An Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Catalyzed by a Novel Brønsted Acidic Ionic Liquid under Solvent-Free Conditions

Y Zhang, B Wang, X Zhang, J Huang, C Liu - Molecules, 2015 - mdpi.com
We report here an efficient and green method for Biginelli condensation reaction of
aldehydes, β-ketoesters and urea or thiourea catalyzed by Brønsted acidic ionic liquid …

Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis

SO Kushch, MV Goryaeva, YV Burgart… - Russian Chemical …, 2023 - Springer
The review is summarized and systematized the published data on the multicomponent
reactions of ethyl trifluoroacetoacetate, carbonyl compounds (aldehydes and ketones), and …