Recurrent miscarriage

DW Branch, C Heuser - … and Infertility: Integrating Modern Clinical and …, 2010 - Springer
Recurrent miscarriage is a common pathology fond in 1% to 5% of reproductively active
couples. This chapter discusses the possible causes of recurrent miscarriage, and …

HLA-G in human reproduction: aspects of genetics, function and pregnancy complications

TVF Hviid - Human reproduction update, 2006 - academic.oup.com
The non-classical human leukocyte antigen (HLA) class Ib genes, HLA-E,-G and-F, are
located on chromosome 6 in the human major histocompatibility complex (MHC). HLA class …

HLA associations and HLA sharing in recurrent miscarriage: a systematic review and meta-analysis

T Meuleman, LELO Lashley, OM Dekkers… - Human immunology, 2015 - Elsevier
Problem The aim of this meta-analysis was to evaluate whether specific maternal HLA
alleles and HLA sharing of couples are associated with the occurrence of recurrent …

Genetic regulation of recurrent spontaneous abortion in humans.

D Vaiman - Biomed J, 2014 - inserm.hal.science
Recurrent pregnancy loss, defined as a pregnancy failure occurring before 24 weeks of
gestation more than two or three times according to most definitions, is a fertility defect …

A systematic analysis of disease-associated variants in the 3′ regulatory regions of human protein-coding genes I: general principles and overview

JM Chen, C Férec, DN Cooper - Human genetics, 2006 - Springer
Abstract The 3′ regulatory regions (3′ RRs) of human genes play an important role in
regulating mRNA 3′ end formation, stability/degradation, nuclear export, subcellular …

The importance of HLA-G expression in embryos, trophoblast cells, and embryonic stem cells

R Rizzo, M Vercammen, H Van De Velde… - Cellular and molecular …, 2011 - Springer
The nonclassical HLA-G molecule is a trophoblast-specific molecule present in almost every
pregnancy. It differs from classical HLA class I molecules by the low degree of allelic variants …

Human leukocyte antigen-G polymorphism in relation to expression, function, and disease

MH Larsen, TVF Hviid - Human immunology, 2009 - Elsevier
Human leukocyte antigen-G (HLA-G) is a nonclassical class Ib molecule belonging to the
major histocompatibility complex. HLA-G appears to play a role in the suppression of …

Human leucocyte antigen class Ib molecules in pregnancy success and early pregnancy loss

M Dahl, TVF Hviid - Human reproduction update, 2012 - academic.oup.com
BACKGROUND The human leucocyte antigen (HLA) class Ib molecules, HLA-E,-F and-G,
are expressed at the materno-fetal interface. Because of the apparent immunoregulatory …

HLA-G Gene Polymorphism in Human Placentas: Possible Association of G*0106 Allele with Preeclampsia and Miscarriage

P Moreau, L Contu, F Alba, S Lai, R Simoes… - Biology of …, 2008 - academic.oup.com
Definite causes for several pathologies of pregnancy remain unknown. In light of several
recent studies, however, diminished or aberrant HLA-G expression may be associated with …

Genetic association between HLA-G 14-bp polymorphism and diseases: A systematic review and meta-analysis

BS de Almeida, YCN Muniz, AH Prompt, EC Castelli… - Human immunology, 2018 - Elsevier
Background HLA-G is an immune checkpoint molecule. Since a differential molecule
expression has been reported even for healthy individuals, many studies have focused on …