Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Canary in the Coal Mine: How Resistance Surveillance in Commensals Could Help Curb the Spread of AMR in Pathogenic Neisseria

M Goytia, CB Wadsworth - Mbio, 2022 - Am Soc Microbiol
Antimicrobial resistance (AMR) is widespread within Neisseria gonorrhoeae populations.
Recent work has highlighted the importance of commensal Neisseria (cN) as a source of …

[HTML][HTML] Distributed genotyping and clustering of Neisseria strains reveal continual emergence of epidemic meningococcus over a century

L Zhong, M Zhang, L Sun, Y Yang, B Wang… - Nature …, 2023 - nature.com
Core genome multilocus sequence typing (cgMLST) is commonly used to classify bacterial
strains into different types, for taxonomical and epidemiological applications. However …

[HTML][HTML] Meningococcal disease in North America: updates from the global meningococcal initiative

EJ Asturias, X Bai, JA Bettinger, R Borrow, DN Castillo… - Journal of Infection, 2022 - Elsevier
This review summarizes the recent Global Meningococcal Initiative (GMI) regional meeting,
which explored meningococcal disease in North America. Invasive meningococcal disease …

[HTML][HTML] Bacterium of one thousand and one variants: genetic diversity of Neisseria gonorrhoeae pathogenicity.

K Kurzyp, OB Harrison - Microbial Genomics, 2023 - microbiologyresearch.org
The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection gonorrhoea.
Although diverse clinical manifestations are associated with gonorrhoea, ranging from …

[HTML][HTML] The Host-Pathogen Interactions and Epicellular Lifestyle of Neisseria meningitidis

A Mikucki, NR McCluskey, CM Kahler - Frontiers in Cellular and …, 2022 - frontiersin.org
Neisseria meningitidis is a gram-negative diplococcus and a transient commensal of the
human nasopharynx. It shares and competes for this niche with a number of other Neisseria …

[HTML][HTML] Antimicrobial Resistance Profiles of Human Commensal Neisseria Species

M Goytia, ST Thompson, SVL Jordan, KA King - Antibiotics, 2021 - mdpi.com
Pathogenic Neisseria gonorrhoeae causes the sexually transmitted infection gonorrhea. N.
gonorrhoeae has evolved high levels of antimicrobial resistance (AR) leading to therapeutic …

[HTML][HTML] Comparative genomics of a novel clade shed light on the evolution of the genus Erysipelothrix and characterise an emerging species

AL Grazziotin, NM Vidal, PG Hoepers, TFM Reis… - Scientific Reports, 2021 - nature.com
Erysipelothrix sp. isolates obtained from a deadly outbreak in farmed turkeys were
sequenced and compared to representatives of the genus. Phylogenetic trees—supported …

[HTML][HTML] Et tu, Neisseria? Conflicts of Interest Between Neisseria Species

R Baerentsen, CM Tang, RM Exley - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Neisseria meningitidis and Neisseria gonorrhoeae are two obligate human pathogens that
have evolved to be uniquely adapted to their host. The meningococcus is frequently carried …

Unveiling the immune dynamics of Neisseria persistent oral colonization

M Alles, M Gunasena, T Zia, A D'Mello… - Infection and …, 2024 - Am Soc Microbiol
Commensal bacteria are crucial in maintaining host physiological homeostasis, immune
system development, and protection against pathogens. Despite their significance, the …