Update on management of diabetic foot ulcers

E Everett, N Mathioudakis - Annals of the New York Academy of …, 2018 - Wiley Online Library
Diabetic foot ulcers (DFUs) are a serious complication of diabetes that results in significant
morbidity and mortality. Mortality rates associated with the development of a DFU are …

Drug delivery systems and materials for wound healing applications

S Saghazadeh, C Rinoldi, M Schot, SS Kashaf… - Advanced drug delivery …, 2018 - Elsevier
Chronic, non-healing wounds place a significant burden on patients and healthcare
systems, resulting in impaired mobility, limb amputation, or even death. Chronic wounds …

Implementing TIMERS: the race against hard-to-heal wounds

L Atkin, Z Bućko, EC Montero, K Cutting… - Journal of wound …, 2019 - magonlinelibrary.com
There may be significant deficiencies in the knowledge among nurses, 38–40 an issue
recognised by many. 41 A survey of community nurses in Ireland found that more than half …

[HTML][HTML] Health economics of diabetic foot ulcer and recent trends to accelerate treatment

A Jodheea-Jutton, S Hindocha, A Bhaw-Luximon - The Foot, 2022 - Elsevier
Diabetic foot ulcer is a preventable complication of diabetes that imposes a significant
burden on the community. It leads to amputation and increased disability if left untreated and …

Skin substitutes as treatment for chronic wounds: Current and future directions

NM Vecin, RS Kirsner - Frontiers in medicine, 2023 - frontiersin.org
Chronic wounds such as diabetic foot ulcers and venous leg ulcers place a significant
burden on the healthcare system and in some cases, have 5-year mortality rates …

Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

A Kerstan, K Dieter, E Niebergall-Roth… - Stem Cell Research & …, 2022 - Springer
Background While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid
infections, amputations and life-threatening complications, DFUs often respond poorly to …

Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review

P Vas, G Rayman, K Dhatariya, V Driver… - Diabetes/metabolism …, 2020 - Wiley Online Library
The management of diabetic foot ulcers (DFU) remains a challenge, and there is continuing
uncertainty concerning optimal approaches to wound healing. The International Working …

Decellularized scaffolds for skin repair and regeneration

M Dussoyer, A Michopoulou, P Rousselle - Applied Sciences, 2020 - mdpi.com
The skin is the largest organ in the body, fulfilling a variety of functions and acting as a
barrier for internal organs against external insults. As for extensive or irreversible damage …

Use of an aseptically processed, dehydrated human amnion and chorion membrane improves likelihood and rate of healing in chronic diabetic foot ulcers: a …

LA DiDomenico, DP Orgill, RD Galiano… - International wound …, 2018 - Wiley Online Library
Amnion and chorion allografts have shown great promise in healing diabetic foot ulcers
(DFUs). Results from an interim analysis of 40 patients have demonstrated the accelerated …

[HTML][HTML] Efficacy and safety of acellular dermal matrix in diabetic foot ulcer treatment: a systematic review and meta-analysis

X Guo, D Mu, F Gao - International Journal of Surgery, 2017 - Elsevier
Background Diabetic foot ulcer (DFU) is a chronic, refractory disease in need of
multidisciplinary endeavour, miscellaneous strategies have been adopted to address this …