An in silico approach to target RNA-dependent RNA polymerase of COVID-19 with naturally occurring phytochemicals

HS Mahrosh, G Mustafa - Environment, Development and Sustainability, 2021 - Springer
The novel coronavirus disease 2019 (COVID-19) was firstly reported from Wuhan city of
China and found as a highly contagious, transmittable and pathogenic viral infection. The …

Virtual screening of phytochemicals by targeting multiple proteins of severe acute respiratory syndrome coronavirus 2: Molecular docking and molecular dynamics …

M Azeem, G Mustafa… - International Journal of …, 2022 - journals.sagepub.com
Objective Medicinal herbs are being investigated for medicationhg development against
SARS-CoV-2 as a rich source of bioactive chemicals. One of the finest approaches for …

Molecular Docking and Simulation-Binding Analysis of Plant Phytochemicals with the Hepatocellular Carcinoma Targets Epidermal Growth Factor Receptor and …

G Mustafa, S Younas, HS Mahrosh, MF Albeshr… - Molecules, 2023 - mdpi.com
Among primary liver cancers, hepatocellular carcinoma (HCC) is one of the most common
forms and it has been categorized as the joint-fourth largest reason of cancer-related deaths …

Investigation of Plant Antimicrobial Peptides against Selected Pathogenic Bacterial Species Using a Peptide‐Protein Docking Approach

G Mustafa, R Mehmood, HS Mahrosh… - BioMed Research …, 2022 - Wiley Online Library
Antimicrobial resistance is the key threat to global health due to high morbidity and mortality.
The alteration of bacterial proteins, enzymatic degradation, and change of membrane …

Integrative network pharmacology and in silico analyses identify the anti-omicron SARS-CoV-2 potential of eugenol

Y Liu - Heliyon, 2023 - cell.com
Eugenol as a natural product is the source of isoniazid, and purified eugenol is extensively
used in the cosmetics industry and the productive processes of edible spices. Accumulating …

Exploring the antihyperglycemic potential of tetrapeptides devised from AdMc1 via different receptor proteins inhibition using in silico approaches

G Mustafa, HS Mahrosh, M Zafar… - International Journal …, 2022 - journals.sagepub.com
Introduction: Diabetes mellitus is a heterogenous group of chronic metabolic disorders that
results due to deficiency in insulin secretion and signalling. Multiple factors held responsible …

In Silico Analysis of Honey Bee Peptides as Potential Inhibitors of Capripoxvirus DNA-Directed RNA Polymerase

G Mustafa, HS Mahrosh, M Salman, M Ali, R Arif… - Animals, 2023 - mdpi.com
Simple Summary The viruses of the Capripoxvirus genus (ie, sheeppox, goatpox, and lumpy
skin disease viruses) pose significant financial threats to the livestock industry, causing …

Computer‐Aided Prediction and Identification of Phytochemicals as Potential Drug Candidates against MERS‐CoV

HS Mahrosh, M Tanveer, R Arif… - BioMed Research …, 2021 - Wiley Online Library
The Middle East respiratory syndrome coronavirus (MERS‐CoV) is the major leading cause
of respiratory infections listed as blueprint of diseases by the World Health Organization. It …

[HTML][HTML] In-silico evaluation of bioactive compounds from selected medicinal plants from Southern Nigeria against hepatitis C virus genotype 1 RNA-directed RNA …

CI Mboto, UO Edet, EN Mbim, WO Ndifon, EE Ebenso… - Scientific African, 2023 - Elsevier
Background At the moment, there is no vaccine for the hepatitis C virus (HCV), despite it
being more infectious than the hepatitis B virus (HBV) and the human immunodeficiency …

Evaluation of phytochemicals from Thymus serpyllum as potential drug candidates to manage oxidative stress in transition dairy cows

J Azhar, A Nadeem, M Javed, HI Ahmad… - Journal of …, 2024 - Taylor & Francis
Dairy cows undergo immense stress and experience autoimmune reactions during the
transition period, majorly due to the generation of ROS in the body. So, pharmacological …