The prokaryotic zinc‐finger: structure, function and comparison with the eukaryotic counterpart

G Malgieri, M Palmieri, L Russo, R Fattorusso… - The FEBS …, 2015 - Wiley Online Library
Classical zinc finger (ZF) domains were thought to be confined to the eukaryotic kingdom
until the transcriptional regulator Ros protein was identified in Agrobacterium tumefaciens …

[HTML][HTML] Host and viral zinc-finger proteins in COVID-19

S Esposito, G D'Abrosca, A Antolak… - International journal of …, 2022 - mdpi.com
An unprecedented effort to tackle the ongoing COVID-19 pandemic has characterized the
activity of the global scientific community over the last two years. Hundreds of published …

The convergent xenogeneic silencer MucR predisposes α-proteobacteria to integrate AT-rich symbiosis genes

WT Shi, B Zhang, ML Li, KH Liu, J Jiao… - Nucleic Acids …, 2022 - academic.oup.com
Bacterial adaptation is largely shaped by horizontal gene transfer, xenogeneic silencing
mediated by lineage-specific DNA bridgers (H-NS, Lsr2, MvaT and Rok), and various anti …

[HTML][HTML] Genome-Wide Identification and Expression Analysis of C3H Zinc Finger Family in Potato (Solanum tuberosum L.)

Z Deng, Z Yang, X Liu, X Dai, J Zhang… - International Journal of …, 2023 - mdpi.com
Transcription factors containing a CCCH structure (C3H) play important roles in plant growth
and development, and their stress response, but research on the C3H gene family in potato …

[HTML][HTML] The Ros/MucR zinc-finger protein family in bacteria: structure and functions

M Janczarek - International Journal of Molecular Sciences, 2022 - mdpi.com
Ros/MucR is a widespread family of bacterial zinc-finger-containing proteins that integrate
multiple functions, such as symbiosis, virulence, transcription regulation, motility, production …

MucR Is Required for Transcriptional Activation of Conserved Ion Transporters to Support Nitrogen Fixation of Sinorhizobium fredii in Soybean Nodules

J Jiao, LJ Wu, B Zhang, Y Hu, Y Li… - Molecular Plant …, 2016 - Am Phytopath Society
To achieve effective symbiosis with legume, rhizobia should fine-tune their background
regulation network in addition to activating key genes involved in nodulation (nod) and …

[HTML][HTML] MucR from Sinorhizobium meliloti: New Insights into Its DNA Targets and Its Ability to Oligomerize

M Slapakova, D Sgambati, L Pirone, V Russo… - International Journal of …, 2023 - mdpi.com
Proteins of the MucR/Ros family play a crucial role in bacterial infection or symbiosis with
eukaryotic hosts. MucR from Sinorhizobium meliloti plays a regulatory role in establishing …

Zinc to cadmium replacement in the prokaryotic zinc-finger domain

G Malgieri, M Palmieri, S Esposito, V Maione… - Metallomics, 2014 - academic.oup.com
Given the similar chemical properties of zinc and cadmium, zinc finger domains have been
often proposed as mediators of the toxic and carcinogenic effects exerted by this xenobiotic …

[HTML][HTML] Identifying the region responsible for Brucella abortus MucR higher-order oligomer formation and examining its role in gene regulation

L Pirone, JE Pitzer, G D'Abrosca, R Fattorusso… - Scientific Reports, 2018 - nature.com
MucR is a member of the Ros/MucR family of prokaryotic zinc-finger proteins found in the α-
proteobacteria which regulate the expression of genes required for the successful …

[HTML][HTML] Substitution of the native Zn (II) with Cd (II), Co (II) and Ni (II) changes the downhill unfolding mechanism of Ros87 to a completely different scenario

R Grazioso, S García-Viñuales, L Russo… - International Journal of …, 2020 - mdpi.com
The structural effects of zinc replacement by xenobiotic metal ions have been widely studied
in several eukaryotic and prokaryotic zinc-finger-containing proteins. The prokaryotic zinc …