Bacteria-based bioactive materials for cancer imaging and therapy

Y Chen, ZH Li, X Zeng, XZ Zhang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Owing to the unique biological functions, bacteria as biological materials have been widely
used in biomedical field. With advances in biotechnology and nanotechnology, various …

Harnessing bacteria for tumor therapy: Current advances and challenges

L Guo, J Ding, W Zhou - Chinese Chemical Letters, 2024 - Elsevier
After a century of standstill, bacteria-based tumor therapy has resurged recently benefiting
from the revolution of tumor immunotherapy, which provides unique solutions to tackle the …

Engineering AraC to make it responsive to light instead of arabinose

E Romano, A Baumschlager, EB Akmeric… - Nature chemical …, 2021 - nature.com
The l-arabinose-responsive AraC and its cognate PBAD promoter underlie one of the most
often used chemically inducible prokaryotic gene expression systems in microbiology and …

CRISPRi-mediated tunable control of gene expression level with engineered single-guide RNA in Escherichia coli

G Byun, J Yang, SW Seo - Nucleic Acids Research, 2023 - academic.oup.com
Precise control of gene expression is essential for flux redistribution in metabolic pathways.
Although the CRISPR interference (CRISPRi) system can effectively repress gene …

Generation of a Gluconobacter oxydans knockout collection for improved extraction of rare earth elements

AM Schmitz, B Pian, S Medin, MC Reid, M Wu… - Nature …, 2021 - nature.com
Bioleaching of rare earth elements (REEs), using microorganisms such as Gluconobacter
oxydans, offers a sustainable alternative to environmentally harmful thermochemical …

New perspectives into Gluconobacter-catalysed biotransformations

M Ripoll, JA Lerma-Escalera… - Biotechnology …, 2023 - Elsevier
Different from other aerobic microorganisms that oxidise carbon sources to water and
carbon dioxide, Gluconobacter catalyses the incomplete oxidation of various substrates with …

Identification of Gradient Promoters of Gluconobacter oxydans and Their Applications in the Biosynthesis of 2-Keto-L-Gulonic Acid

Y Chen, L Liu, S Yu, J Li, J Zhou… - Frontiers in Bioengineering …, 2021 - frontiersin.org
The acetic acid bacterium Gluconobacter oxydans is known for its unique incomplete
oxidation and therefore widely applied in the industrial production of many compounds, eg …

Directional enhancement of 2-keto-gluconic acid production from enzymatic hydrolysate by acetic acid-mediated bio-oxidation with Gluconobacter oxydans

L Dai, W Jiang, R Jia, X Zhou, Y Xu - Bioresource Technology, 2022 - Elsevier
An acetic acid-mediated bio-oxidation strategy with Gluconobacter oxydans was developed
to produce valuable 2-ketogluconic acid from lignocellulosic biomass. Metabolically …

Systematic part transfer by extending a modular toolkit to diverse bacteria

KW Keating, EM Young - ACS Synthetic Biology, 2023 - ACS Publications
It is impractical to develop a new parts collection for every potential host organism. It is well-
established that gene expression parts, like genes, are qualitatively transferable, but there is …

Highly tunable TetR-dependent target gene expression in the acetic acid bacterium Gluconobacter oxydans

PM Fricke, M LŘrkens, M HŘnnefeld… - Applied microbiology …, 2021 - Springer
For the acetic acid bacterium (AAB) Gluconobacter oxydans only recently the first tight
system for regulatable target gene expression became available based on the heterologous …