[HTML][HTML] B vitamins and one-carbon metabolism: implications in human health and disease
Vitamins B9 (folate) and B12 are essential water-soluble vitamins that play a crucial role in
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …
Methylmalonic acid in aging and disease
Metabolic byproducts have conventionally been disregarded as waste products without
functions. In this opinion article, we bring to light the multifaceted role of methylmalonic acid …
functions. In this opinion article, we bring to light the multifaceted role of methylmalonic acid …
[HTML][HTML] Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia
A Luciani, MCS Denley, LP Govers… - Cellular and Molecular …, 2021 - Springer
Mitochondria—the intracellular powerhouse in which nutrients are converted into energy in
the form of ATP or heat—are highly dynamic, double-membraned organelles that harness a …
the form of ATP or heat—are highly dynamic, double-membraned organelles that harness a …
Stable Co (II)-based coordination polymer as fluorescence sensor for the discriminative sensing of biomarker methylmalonic acid
R Luo, CG Xu, DM Zhang, LL Wang, RX Wu, GB Chen… - Talanta, 2023 - Elsevier
Three novel Co-based coordination polymers including {[Co (L)(μ 3-O) 1/3] 2} n (1),{[Co
(L)(bimb)]} n (2) and {[Co (L)(bimmb) 1/2]} n (3)(H 2 L= 2, 6-di (4-carboxylphenyl)-4-(4 …
(L)(bimb)]} n (2) and {[Co (L)(bimmb) 1/2]} n (3)(H 2 L= 2, 6-di (4-carboxylphenyl)-4-(4 …
[HTML][HTML] Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
C Buoso, M Seifert, M Lang, CM Griffith… - Neurobiology of …, 2024 - Elsevier
Imbalances of iron and dopamine metabolism along with mitochondrial dysfunction have
been linked to the pathogenesis of Parkinson's disease (PD). We have previously suggested …
been linked to the pathogenesis of Parkinson's disease (PD). We have previously suggested …
Neurologic outcome following liver transplantation for methylmalonic aciduria
D Martinelli, G Catesini, B Greco… - Journal of Inherited …, 2023 - Wiley Online Library
Liver and liver/kidney transplantation are increasingly used in methylmalonic aciduria, but
little is known on their impact on CNS. The effect of transplantation on neurological outcome …
little is known on their impact on CNS. The effect of transplantation on neurological outcome …
[HTML][HTML] Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency
Methylmalonic aciduria (MMA) is an inborn error of metabolism with multiple monogenic
causes and a poorly understood pathogenesis, leading to the absence of effective causal …
causes and a poorly understood pathogenesis, leading to the absence of effective causal …
The efficacy of anti‐proteolytic peptide R7I in intestinal inflammation, function, microbiota, and metabolites by multi‐omics analysis in murine bacterial enteritis
T Sun, X Liu, Y Su, Z Wang, B Cheng… - Bioengineering & …, 2023 - Wiley Online Library
Increased antibiotic resistance poses a major limitation in tackling inflammatory bowel
disease and presents a large challenge for global health care. Antimicrobial peptides …
disease and presents a large challenge for global health care. Antimicrobial peptides …
[HTML][HTML] Applications of Boolean modeling to study the dynamics of a complex disease and therapeutics responses
AA Hemedan, R Schneider… - Frontiers in bioinformatics, 2023 - frontiersin.org
Computational modeling has emerged as a critical tool in investigating the complex
molecular processes involved in biological systems and diseases. In this study, we apply …
molecular processes involved in biological systems and diseases. In this study, we apply …
An ultrastable zinc-based organic framework as a recyclable luminescent probe for methylmalonic acid detection
X Zhang, Y Tian, J Shi, X Kang, Z Liu - Journal of Materials Chemistry …, 2022 - pubs.rsc.org
Methylmalonic acid (MMA) as a functional marker of vitamin B12 deficiency has attracted
extensive attention. However, the highly selective and sensitive detection of MMA in a …
extensive attention. However, the highly selective and sensitive detection of MMA in a …