Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Combating implant infections: shifting focus from bacteria to host

S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections

MS Linz, A Mattappallil, D Finkel, D Parker - Antibiotics, 2023 - mdpi.com
The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in
skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused …

[HTML][HTML] NOD1 and NOD2: signaling, host defense, and inflammatory disease

R Caruso, N Warner, N Inohara, G Núñez - Immunity, 2014 - cell.com
The nucleotide-binding oligomerization domain (NOD) proteins NOD1 and NOD2, the
founding members of the intracellular NOD-like receptor family, sense conserved motifs in …

Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

BJ Berube, J Bubeck Wardenburg - Toxins, 2013 - mdpi.com
Staphylococcus aureus secretes a number of host-injurious toxins, among the most
prominent of which is the small β-barrel pore-forming toxin α-hemolysin. Initially named …

[HTML][HTML] Pathogenesis of Staphylococcus aureus abscesses

SD Kobayashi, N Malachowa, FR DeLeo - The American journal of …, 2015 - Elsevier
Staphylococcus aureus causes many types of human infections and syndromes—most
notably skin and soft tissue infections. Abscesses are a frequent manifestation of S. aureus …

NOD proteins: regulators of inflammation in health and disease

DJ Philpott, MT Sorbara, SJ Robertson… - Nature Reviews …, 2014 - nature.com
Entry of bacteria into host cells is an important virulence mechanism. Through peptidoglycan
recognition, the nucleotide-binding oligomerization domain (NOD) proteins NOD1 and …

NOD1 and NOD2 in inflammation, immunity and disease

T Mukherjee, ES Hovingh, EG Foerster… - Archives of biochemistry …, 2019 - Elsevier
NOD1 and NOD2 are related intracellular sensors of bacterial peptidoglycan and belong to
the Nod-like receptor (NLR) family of innate immune proteins that play fundamental and …

NOD1 and NOD2 in inflammatory and infectious diseases

BC Trindade, GY Chen - Immunological reviews, 2020 - Wiley Online Library
It has been long recognized that NOD1 and NOD2 are critical players in the host immune
response, primarily by their sensing bacterial peptidoglycan‐conserved motifs. Significant …

Interactions of Methicillin Resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in Polymicrobial Wound Infection

I Pastar, AG Nusbaum, J Gil, SB Patel, J Chen… - PloS one, 2013 - journals.plos.org
Understanding the pathology resulting from Staphylococcus aureus and Pseudomonas
aeruginosa polymicrobial wound infections is of great importance due to their ubiquitous …