Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

Body diffusion kurtosis imaging: basic principles, applications, and considerations for clinical practice

AB Rosenkrantz, AR Padhani… - Journal of Magnetic …, 2015 - Wiley Online Library
Technologic advances enable performance of diffusion‐weighted imaging (DWI) at ultrahigh
b‐values, where standard monoexponential model analysis may not apply. Rather, non …

[HTML][HTML] Weakly-supervised convolutional neural networks for multimodal image registration

Y Hu, M Modat, E Gibson, W Li, N Ghavami… - Medical image …, 2018 - Elsevier
One of the fundamental challenges in supervised learning for multimodal image registration
is the lack of ground-truth for voxel-level spatial correspondence. This work describes a …

Diffusion MRI of cancer: From low to high b‐values

L Tang, XJ Zhou - Journal of Magnetic Resonance Imaging, 2019 - Wiley Online Library
Following its success in early detection of cerebral ischemia, diffusion‐weighted imaging
(DWI) has been increasingly used in cancer diagnosis and treatment evaluation. These …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

Changes in epithelium, stroma, and lumen space correlate more strongly with Gleason pattern and are stronger predictors of prostate ADC changes than cellularity …

A Chatterjee, G Watson, E Myint, P Sved, M McEntee… - Radiology, 2015 - pubs.rsna.org
Purpose To investigate the hypothesis that the clinically observed decrease in apparent
diffusion coefficient (ADC) at diffusion-weighted magnetic resonance imaging with …

How rapid advances in imaging are defining the future of precision radiation oncology

L Beaton, S Bandula, MN Gaze, RA Sharma - British journal of cancer, 2019 - nature.com
Imaging has an essential role in the planning and delivery of radiotherapy. Recent advances
in imaging have led to the development of advanced radiotherapy techniques—including …

Time-dependent diffusion MRI in cancer: tissue modeling and applications

O Reynaud - Frontiers in Physics, 2017 - frontiersin.org
In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been
recognized as a useful and sensitive surrogate for cell density, paving the way for non …

Diagnosis of prostate cancer with noninvasive estimation of prostate tissue composition by using hybrid multidimensional MR imaging: a feasibility study

A Chatterjee, RM Bourne, S Wang, A Devaraj… - Radiology, 2018 - pubs.rsna.org
Purpose To evaluate whether compartmental analysis by using hybrid multidimensional
magnetic resonance (MR) imaging can be used to diagnose prostate cancer and determine …

Evaluation of diffusion kurtosis imaging versus standard diffusion imaging for detection and grading of peripheral zone prostate cancer

MC Roethke, TA Kuder, TH Kuru, M Fenchel… - Investigative …, 2015 - journals.lww.com
Objectives The purpose of the study was to evaluate and validate diffusion kurtosis imaging
(DKI) for detection grading of peripheral zone prostate cancer (PCa) compared with …