Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy
Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …
arising as important players in various biological pathways. They have received extensive …
Prevention and early detection of prostate cancer
Prostate cancer is a common malignancy in men and the worldwide burden of this disease
is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control …
is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control …
A novel urine exosome gene expression assay to predict high-grade prostate cancer at initial biopsy
J McKiernan, MJ Donovan, V O'Neill, S Bentink… - JAMA …, 2016 - jamanetwork.com
Importance Overdiagnosis and overtreatment of indolent prostate cancer (PCA) is a serious
health issue in most developed countries. There is an unmet clinical need for noninvasive …
health issue in most developed countries. There is an unmet clinical need for noninvasive …
Urine TMPRSS2: ERG plus PCA3 for individualized prostate cancer risk assessment
SA Tomlins, JR Day, RJ Lonigro, DH Hovelson… - European urology, 2016 - Elsevier
Abstract Background TMPRSS2: ERG (T2: ERG) and prostate cancer antigen 3 (PCA3) are
the most advanced urine-based prostate cancer (PCa) early detection biomarkers. Objective …
the most advanced urine-based prostate cancer (PCa) early detection biomarkers. Objective …
Genomic markers in prostate cancer decision making
V Cucchiara, MR Cooperberg, M Dall'Era, DW Lin… - European urology, 2018 - Elsevier
Context Although the widespread use of prostate-specific antigen (PSA) has led to an early
detection of prostate cancer (PCa) and a reduction of metastatic disease at diagnosis, PSA …
detection of prostate cancer (PCa) and a reduction of metastatic disease at diagnosis, PSA …
PSA and beyond: alternative prostate cancer biomarkers
S Saini - Cellular Oncology, 2016 - Springer
Background The use of biomarkers for prostate cancer screening, diagnosis and prognosis
has the potential to improve the clinical management of the patients. Owing to inherent …
has the potential to improve the clinical management of the patients. Owing to inherent …
The crucial role of multiomic approach in cancer research and clinically relevant outcomes
M Lu, X Zhan - EPMA Journal, 2018 - Springer
Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …
research. Some remarkable achievements have been made; however, the exact …
Emerging role of oncogenic long noncoding RNA as cancer biomarkers
The view of long noncoding RNAs as nonfunctional “garbage” has been definitely outdated
by the large body of evidence indicating this class of ncRNAs as “golden junk”, especially in …
by the large body of evidence indicating this class of ncRNAs as “golden junk”, especially in …
A rich array of prostate cancer molecular biomarkers: opportunities and challenges
I Kohaar, G Petrovics, S Srivastava - International journal of molecular …, 2019 - mdpi.com
Prostate cancer is the most prevalent non-skin cancer in men and is the leading cause of
cancer-related death. Early detection of prostate cancer is largely determined by a widely …
cancer-related death. Early detection of prostate cancer is largely determined by a widely …
Identification of a candidate gene panel for the early diagnosis of prostate cancer
GHJM Leyten, D Hessels, FP Smit, SA Jannink… - Clinical cancer …, 2015 - AACR
Abstract Purpose: Serum PSA (sPSA) testing has led to the identification of patients with
indolent prostate cancer, and inevitably overtreatment has become a concern. Progensa …
indolent prostate cancer, and inevitably overtreatment has become a concern. Progensa …