[HTML][HTML] Fish toxicity testing for identification of thyroid disrupting chemicals

ZC Dang, M Arena, A Kienzler - Environmental Pollution, 2021 - Elsevier
Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of
endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals …

AOP report: Thyroperoxidase inhibition leading to altered visual function in fish via altered retinal layer structure

L Gölz, L Baumann, P Pannetier… - Environmental …, 2022 - Wiley Online Library
Thyroid hormones (THs) are involved in the regulation of many important physiological and
developmental processes, including vertebrate eye development. Thyroid hormone system …

[HTML][HTML] A crystal-clear zebrafish for in vivo imaging

P Antinucci, R Hindges - Scientific reports, 2016 - nature.com
The larval zebrafish (Danio rerio) is an excellent vertebrate model for in vivo imaging of
biological phenomena at subcellular, cellular and systems levels. However, the optical …

Thyroid hormone disruption by bis-(2-ethylhexyl) phthalate (DEHP) and bis-(2-ethylhexyl) adipate (DEHA) in Japanese medaka Oryzias latipes

Y Horie, M Nomura, BR Ramaswamy, H Harino… - Aquatic Toxicology, 2022 - Elsevier
Pollution of water bodies with plasticizers is a serious environmental problem worldwide. In
this study, we investigated the effects of plasticizers bis-(2-ethylhexyl) phthalate (DEHP) and …

Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish

I Van Dingenen, L Vergauwen, AC Haigis… - Aquatic Toxicology, 2023 - Elsevier
Thyroid hormone system disruption (THSD) negatively affects multiple developmental
processes and organs. In fish, inhibition of deiodinases, which are enzymes crucial for (in) …

Thyroid disruption in zebrafish (Danio rerio) larvae: Different molecular response patterns lead to impaired eye development and visual functions

L Baumann, A Ros, K Rehberger, SCF Neuhauss… - Aquatic Toxicology, 2016 - Elsevier
The vertebrate thyroid system is important for multiple developmental processes, including
eye development. Thus, its environmentally induced disruption may impact important fitness …

Reversibility of Thyroid Hormone System–Disrupting Effects on Eye and Thyroid Follicle Development in Zebrafish (Danio rerio) Embryos

P Pannetier, R Poulsen, L Gölz… - Environmental …, 2023 - Wiley Online Library
Early vertebrate development is partially regulated by thyroid hormones (THs).
Environmental pollutants that interact with the TH system (TH system–disrupting chemicals …

Nano-sized polystyrene plastic particles affect many cancer-related biological processes even in the next generations; zebrafish modeling

E Sulukan, O Şenol, A Baran, M Kankaynar… - Science of The Total …, 2022 - Elsevier
With the ever-increasing plastic pollution, the nano-sized plastic particles that are constantly
released from the main materials have a greater potential threat. Studies continue on how to …

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

XK Chen, JSK Kwan, RCC Chang, ACH Ma - Autophagy, 2021 - Taylor & Francis
phenyl 2-thiourea (PTU) is a Tyr (tyrosinase) inhibitor that is extensively used to block
pigmentation and improve optical transparency in zebrafish (Danio rerio) embryo. Here, we …

Effects of 25 thyroid hormone disruptors on zebrafish embryos: A literature review of potential biomarkers

K Spaan, AC Haigis, J Weiss, J Legradi - Science of the Total Environment, 2019 - Elsevier
It is estimated that many organic compounds found in our environment can interfere with the
thyroid system and act as thyroid hormone (TH) disruptor. Despite that, there is a clear lack …