The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and
whose composition changes as a function of an animal's physiological state. Ciliated …

Neurobiologists have long sought to understand how circuits in the nervous system are
organized to generate the precise neural outputs that underlie particular behaviours. The …

The zebrafish is a leading model for studies of vertebrate development and genetics. Its
embryonic motor behaviors are easy to assess (eg for mutagenic screens), the embryos …

Summary 1 Nearly all fish evade predation strikes by rapidly accelerating out of the strike
path, a behaviour called the fast‐start evasion response. The many studies investigating …

Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by a loss
of α motoneurons in the spinal cord. SMA is caused by low levels of the ubiquitously …

Animals move over a range of speeds by using rhythmic networks of neurons located in the
spinal cord,,,,,. Here we use electrophysiology and in vivo imaging in larval zebrafish (Danio …

Neuromechanics seeks to understand how muscles, sense organs, motor pattern
generators, and brain interact to produce coordinated movement, not only in complex terrain …

Vertebrate locomotion at different speeds is driven by descending excitatory connections to
central pattern generators in the spinal cord. To investigate how these inputs determine …

Regulation of myelination by oligodendrocytes in the CNS has important consequences for
higher-order nervous system function (eg,[1–4]), and there is growing consensus that …

Motor systems must continuously adapt their output to maintain a desired trajectory. While
the spinal circuits underlying rhythmic locomotion are well described, little is known about …