The Gag proteins of HIV-1, like those of other retroviruses, are necessary and sufficient for
the assembly of virus-like particles. The roles played by HIV-1 Gag proteins during the life …

The HIV genome encodes a small number of viral proteins (ie, 16), invariably establishing
cooperative associations among HIV proteins and between HIV and host proteins, to invade …

Gag, the primary structural protein of HIV-1, is recruited to the plasma membrane for virus
assembly by its matrix (MA) domain. Gag is subsequently cleaved into its component …

The human immunodeficiency virus type 1 (HIV-1) assembly-and-release pathway begins
with the targeting of the Gag precursor to the site of virus assembly. The molecular …

Human immunodeficiency virus type 1 (HIV-1) particle formation and the subsequent
initiation of protease-mediated maturation occur predominantly on the plasma membrane …

Binding of the human immunodeficiency virus type 1 (HIV-1) Gag protein precursor,
Pr55Gag, to membrane is an indispensable step in virus assembly. Previously, we reported …

Gag proteins direct the process of retroviral particle assembly and form the major protein
constituents of the viral core. The matrix region of the HIV-1 Gag polyprotein plays a critical …

Several critical steps in the replication cycle of human immunodeficiency virus type 1 (HIV-1)–
entry, assembly and budding–are complex processes that take place at the plasma …

The p6 domain of human immunodeficiency virus type 1 (HIV-1) is located at the C terminus
of the Gag precursor protein Pr55Gag. Previous studies indicated that p6 plays a critical role …

During the late stage of the viral life cycle, HIV-1 Gag assembles into a spherical immature
capsid, and undergoes budding, release, and maturation. Here we review events involved in …