Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics
SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
causes many severe acute and chronic infections with high morbidity, and mortality rates as …
Enhanced annotations and features for comparing thousands of Pseudomonas genomes in the Pseudomonas genome database
Abstract The Pseudomonas Genome Database (http://www. pseudomonas. com) is well
known for the application of community-based annotation approaches for producing a high …
known for the application of community-based annotation approaches for producing a high …
The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity
The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …
Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis
MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …
Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections
CH Goss, Y Kaneko, L Khuu, GD Anderson… - Science translational …, 2018 - science.org
The lack of new antibiotics is among the most critical challenges facing medicine. The
problem is particularly acute for Gram-negative bacteria. An unconventional antibiotic …
problem is particularly acute for Gram-negative bacteria. An unconventional antibiotic …
Mixed strain pathogen populations accelerate the evolution of antibiotic resistance in patients
J Diaz Caballero, RM Wheatley, N Kapel… - Nature …, 2023 - nature.com
Antibiotic resistance poses a global health threat, but the within-host drivers of resistance
remain poorly understood. Pathogen populations are often assumed to be clonal within …
remain poorly understood. Pathogen populations are often assumed to be clonal within …
Pseudomonas predators: understanding and exploiting phage–host interactions
J De Smet, H Hendrix, BG Blasdel… - Nature Reviews …, 2017 - nature.com
Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …
[HTML][HTML] Recent advances in understanding Pseudomonas aeruginosa as a pathogen
J Klockgether, B Tümmler - F1000Research, 2017 - ncbi.nlm.nih.gov
The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen
causing acute and chronic infections in predisposed human subjects. Here we review recent …
causing acute and chronic infections in predisposed human subjects. Here we review recent …
Applications of machine learning to the problem of antimicrobial resistance: an emerging model for translational research
Antimicrobial resistance (AMR) remains one of the most challenging phenomena of modern
medicine. Machine learning (ML) is a subfield of artificial intelligence that focuses on the …
medicine. Machine learning (ML) is a subfield of artificial intelligence that focuses on the …