Inflammatory bowel disease (IBD) is an immune-mediated disease of the intestinal tract, with
complex pathophysiology involving genetic, environmental, microbiome, immunological and …

Protein biochips are at the heart of many medical and bioanalytical applications. Increasing
interest has been focused on surface activation and subsequent functionalization strategies …

Developing therapeutic antibodies is laborious and costly. Here we report a method for
antibody discovery that leverages the Illumina HiSeq platform to, within 3 days, screen in the …

Introduction Plummeting sequencing costs have led to a great increase in the number of
personal genomes. Interpreting the large number of variants in them, particularly in …

The protein Cdc45 plays a critical but poorly understood role in the initiation and elongation
stages of eukaryotic DNA replication. To study Cdc45's function in DNA replication, we …

The study of biological systems relies to a large extent on DNA cloning technologies
enabling the analysis of recombinant genes through transgenic research. In this context, the …

Since the early 2000s, extensive research has been performed to address numerous
challenges in biochip and biosensor fabrication in order to use them for various biomedical …

Understanding complex functional mechanisms requires the global and parallel analysis of
different cellular processes. DNA microarrays have become synonymous with this kind of …

Cell-free systems offer a promising approach to engineer biology since their open nature
allows for well-controlled and characterized reaction conditions. In this review, we discuss …

Autoantibodies against autologus tumor‐associated antigens have been detected in the
asymptomatic stage of cancer and can thus serve as biomarkers for early cancer diagnosis …