Meddling with metal sensors: Fur-family proteins as signaling hubs

CH Steingard, JD Helmann - Journal of Bacteriology, 2023 - Am Soc Microbiol
The ferric uptake regulator (Fur) protein is the founding member of the FUR superfamily of
metalloregulatory proteins that control metal homeostasis in bacteria. FUR proteins regulate …

The impact of transition metals on bacterial plant disease

H Fones, GM Preston - FEMS Microbiology Reviews, 2013 - academic.oup.com
Metals play essential roles in many biological processes but are toxic when present in
excess. This makes their transport and homoeostatic control of particular importance to living …

Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation

J Butcher, S Sarvan, JS Brunzelle… - Proceedings of the …, 2012 - National Acad Sciences
The full regulatory potential of the ferric uptake regulator (Fur) family of proteins remains
undefined despite over 20 years of study. We report herein an integrated approach that …

The metabolic regulator CodY links Listeria monocytogenes metabolism to virulence by directly activating the virulence regulatory gene prfA

L Lobel, N Sigal, I Borovok, BR Belitsky… - Molecular …, 2015 - Wiley Online Library
Metabolic adaptations are critical to the ability of bacterial pathogens to grow within host
cells and are normally preceded by sensing of host‐specific metabolic signals, which in turn …

Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa

JR Wiens, AI Vasil, MJ Schurr, ML Vasil - MBio, 2014 - Am Soc Microbiol
Pseudomonas aeruginosa strains of non-cystic fibrosis (non-CF) origin do not produce
significant amounts of extracellular alginate and are nonmucoid. In CF, such isolates can …

Crp Is a Global Regulator of Antibiotic Production in Streptomyces

C Gao, Hindra, D Mulder, C Yin, MA Elliot - MBio, 2012 - Am Soc Microbiol
Cyclic AMP receptor protein (Crp) is a transcription regulator controlling diverse cellular
processes in many bacteria. In Streptomyces coelicolor, it is well established that Crp plays …

Next-generation sequencing technologies and their impact on microbial genomics

BM Forde, PW O'Toole - Briefings in functional genomics, 2013 - academic.oup.com
Next-generation sequencing technologies have had a dramatic impact in the field of
genomic research through the provision of a low cost, high-throughput alternative to …

Ca2+-Induced Two-Component System CvsSR Regulates the Type III Secretion System and the Extracytoplasmic Function Sigma Factor AlgU in Pseudomonas …

MR Fishman, J Zhang, PA Bronstein… - Journal of …, 2018 - Am Soc Microbiol
Two-component systems (TCSs) of bacteria regulate many different aspects of the bacterial
life cycle, including pathogenesis. Most TCSs remain uncharacterized, with no information …

Molecular networks in plant–pathogen holobiont

T Nobori, A Mine, K Tsuda - FEBS letters, 2018 - Wiley Online Library
Plant immune receptors enable detection of a multitude of microbes including pathogens.
The recognition of microbes activates various plant signaling pathways, such as those …

The Effect of Iron Limitation on the Transcriptome and Proteome of Pseudomonas fluorescens Pf-5

CK Lim, KA Hassan, SG Tetu, JE Loper, IT Paulsen - PLoS one, 2012 - journals.plos.org
One of the most important micronutrients for bacterial growth is iron, whose bioavailability in
soil is limited. Consequently, rhizospheric bacteria such as Pseudomonas fluorescens …