Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen
A Maitra, T Munshi, J Healy, LT Martin… - FEMS microbiology …, 2019 - academic.oup.com
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis,
remains one of the leading causes of mortality across the world. There is an urgent …
remains one of the leading causes of mortality across the world. There is an urgent …
Challenges of antibacterial discovery
LL Silver - Clinical microbiology reviews, 2011 - Am Soc Microbiol
The discovery of novel small-molecule antibacterial drugs has been stalled for many years.
The purpose of this review is to underscore and illustrate those scientific problems unique to …
The purpose of this review is to underscore and illustrate those scientific problems unique to …
A review on nano-antimicrobials: metal nanoparticles, methods and mechanisms
E Hoseinzadeh, P Makhdoumi, P Taha… - Current drug …, 2017 - ingentaconnect.com
Nanotechnology is a scientific and engineering technology conducted at the nano-scale,
such as in the fields of compound fabric manufacturing, food processing, agricultural …
such as in the fields of compound fabric manufacturing, food processing, agricultural …
[图书][B] Practical handbook of microbiology
LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …
knowledge and practical information about working with microorganisms. Useful to anyone …
Structural perspective of peptidoglycan biosynthesis and assembly
AL Lovering, SS Safadi… - Annual review of …, 2012 - annualreviews.org
The peptidoglycan biosynthetic pathway is a critical process in the bacterial cell and is
exploited as a target for the design of antibiotics. This pathway culminates in the production …
exploited as a target for the design of antibiotics. This pathway culminates in the production …
Cell envelope stress response in Gram-positive bacteria
S Jordan, MI Hutchings… - FEMS microbiology …, 2008 - academic.oup.com
The bacterial cell envelope is the first and major line of defence against threats from the
environment. It is an essential and yet vulnerable structure that gives the cell its shape and …
environment. It is an essential and yet vulnerable structure that gives the cell its shape and …
Bacterial cell wall assembly: still an attractive antibacterial target
The development of new antibacterial agents to combat worsening antibiotic resistance is
still a priority area in anti-infectives research, but in the post-genomic era it has been more …
still a priority area in anti-infectives research, but in the post-genomic era it has been more …
FtsN maintains active septal cell wall synthesis by forming a processive complex with the septum-specific peptidoglycan synthases in E. coli
FtsN plays an essential role in promoting the inward synthesis of septal peptidoglycan (sPG)
by the FtsWI complex during bacterial cell division. How it achieves this role is unclear. Here …
by the FtsWI complex during bacterial cell division. How it achieves this role is unclear. Here …
A road map for prioritizing warheads for cysteine targeting covalent inhibitors
Targeted covalent inhibitors have become an integral part of a number of therapeutic
protocols and are the subject of intense research. The mechanism of action of these …
protocols and are the subject of intense research. The mechanism of action of these …
Challenges of antibacterial discovery revisited
MN Gwynn, A Portnoy, SF Rittenhouse… - Annals of the New …, 2010 - Wiley Online Library
The discovery of novel antibiotic classes has not kept pace with the growing threat of
bacterial resistance. Antibiotic candidates that act at new targets or via distinct mechanisms …
bacterial resistance. Antibiotic candidates that act at new targets or via distinct mechanisms …