Convergence as a phenomenon in molecular evolution is an issue that confuses many
discussions. Often the problem is that not enough care is taken to state exactly what kind of …

Infection by human immunodeficiency virus type 1 (HIV-1) leads to progressive destruction
of the CD4+ T-cell subset, resulting in immune deficiency and AIDS. The specific binding of …

Development of a preventive immunogen for human immunodeficiency virus (HIV) infection
is a national priority. The complexities associated with HIV host-virus interactions, coupled …

The mechanisms of immune suppression by the human immunodeficiency virus, HIV-1, are
more complex than simple helper T cell deletion via infection and viral-induced lysis. Since …

Background While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T
lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that …

T cell immunity is of central importance in recovery from primary infection and protection
against recurrent infection with viruses. 1 Hence dysregulation and suppression of T cell …

The immune defects characterizing infection with the human immunodeficiency virus (HIV)
and culminating in the acquired immune deficiency syndrome (AIDS) are the result of a …

According to the multiple criteria used, the consensus sequences of HIV-1 gp120 and
immunoglobulin heavy chain variable segment, which is more than 40 amino acids long …

Antibodies to the carboxy-terminal constant (C5) region 5 of the HIV-1 envelope glycoprotein
gp120 have previously been associated with slow disease progression. This is one of the …

Recent information on the efficacy of anti-retroviral therapy and vaccination strategies has
been disappointing as well as confusing. The recently announced Concorde study …