Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and
expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) …

Pancreatic cancer is a leading cause of cancer death worldwide and its global burden has
more than doubled over the past 25 years. The highest incidence regions for pancreatic …

We assembled an ancestrally diverse collection of genome-wide association studies
(GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls …

The past 50 years have seen a growing ageing population with an increasing prevalence of
type 2 diabetes mellitus (T2DM); now, nearly half of all individuals with diabetes mellitus are …

Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has changed many social,
economic, environmental and healthcare determinants of health. We applied an ensemble …

Insulin resistance is the pivotal pathogenic component of many metabolic diseases,
including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of …

Background & Aims There were an estimated 4.8 million new cases of gastrointestinal (GI)
cancers and 3.4 million related deaths, worldwide, in 2018. GI cancers account for 26% of …

Loss of functional β-cell mass is the key mechanism leading to the two main forms of
diabetes mellitus—type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) …