Somatostatin receptors and analogs in pheochromocytoma and paraganglioma: old players in a new precision medicine world

M Patel, I Tena, A Jha, D Taieb, K Pacak - Frontiers in Endocrinology, 2021 - frontiersin.org
Neuroendocrine tumors overexpress somatostatin receptors, which serve as important and
unique therapeutic targets for well-differentiated advanced disease. This overexpression is a …

[HTML][HTML] A review of advances in the last decade on targeted cancer therapy using 177Lu: Focusing on 177Lu produced by the direct neutron activation route

R Chakravarty, S Chakraborty - American Journal of Nuclear …, 2021 - ncbi.nlm.nih.gov
Abstract Lutetium-177 [T½= 6.76 d; E β (max)= 0.497 MeV; maximum tissue range~ 2.5 mm;
208 keV γ-ray] is one of the most important theranostic radioisotope used for the …

[HTML][HTML] Electrochemical separation and purification of no-carrier-added 177Lu for radiopharmaceutical preparation: Translation from bench to bed

S Patra, R Chakravarty, K Singh, KV Vimalnath… - Chemical Engineering …, 2023 - Elsevier
The entry of no-carrier-added (NCA) 177 Lu in the arena of clinical nuclear medicine has
revolutionized the practice of targeted radionuclide tumor therapy. In this study, we report the …

Long-term outcome of indigenous 177Lu-DOTATATE PRRT in patients with Metastatic Advanced Neuroendocrine Tumours: a single institutional observation in a …

K Sitani, RV Parghane, S Talole… - The British journal of …, 2021 - academic.oup.com
Objectives: Assessment of long-term outcome and toxicity of indigenous 177Lu-DOTATATE
PRRT in patients of metastatic/advanced NETs in a large tertiary-care PRRT setting …

Need for enrichment of lutetium isotope and design of a laser based separator module

A Majumder, AK Pulhani, A Ghosh, P Singh… - Applied Radiation and …, 2023 - Elsevier
Lutetium-177 radio-pharmaceutical has become an important theranostic candidate in
cancer treatment. Its availability from bench-to-bed requires strategic implementation of …

Case report: octreotide plus CVD chemotherapy for the treatment of multiple metastatic paragangliomas after double resection for functional bladder paraganglioma …

Z Wang, F Liu, C Li, H Yuan, Y Xiang, C Wei… - Frontiers in …, 2023 - frontiersin.org
Background Metastatic pheochromocytomas and paragangliomas are rare neuroendocrine
tumors with a poor prognosis. Bladder paraganglioma concomitant with urothelial papilloma …

Peptide receptor radionuclide therapy in neuroendocrine neoplasms and related tumors: from fundamentals to personalization and the newer experimental …

S Loharkar, S Basu - Expert Review of Precision Medicine and …, 2023 - Taylor & Francis
ABSTRACT Introduction Peptide Receptor Radionuclide Therapy (PRRT) is a type of
molecular-targeted endo-radionuclide therapy in which unsealed radiolabelled somatostatin …

Discordance between histopathologic grading and dual-tracer PET/CT findings in metastatic NETs and outcome of 177Lu-DOTATATE PRRT: does in vivo molecular …

A Adnan, S Basu - Journal of Nuclear Medicine Technology, 2022 - Soc Nuclear Med
Discordance between histopathologic grading and dual-tracer PET/CT (68Ga-DOTATATE
and 18F-FDG) findings in neuroendocrine tumors (NETs), though not typical, can be …

Radiolabeled Somatostatin Analogs for Cancer Imaging

AK Nazar, S Basu - Seminars in Nuclear Medicine, 2024 - Elsevier
Somatostatin receptors (SSTR) are expressed by many tumours especially those related to
neuro-endocrine origin and molecular functional imaging of SSTR expression using …

Radiation and radioisotopes for human healthcare applications.

S Banerjee, S Basu, AD Baheti… - Current Science …, 2022 - search.ebscohost.com
The use of radiation and radioisotopes in human healthcare has been one of the early
developments in the non-power applications of nuclear science. The field encompasses …