[HTML][HTML] Microglia and astrocytes underlie neuroinflammation and synaptic susceptibility in autism spectrum disorder
Y Xiong, J Chen, Y Li - Frontiers in Neuroscience, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with onset in
childhood. The mechanisms underlying ASD are unclear. In recent years, the role of …
childhood. The mechanisms underlying ASD are unclear. In recent years, the role of …
[HTML][HTML] Postsynaptic autism spectrum disorder genes and synaptic dysfunction
P Bonsi, A De Jaco, L Fasano, P Gubellini - Neurobiology of disease, 2022 - Elsevier
This review provides an overview of the synaptic dysfunction of neuronal circuits and the
ensuing behavioral alterations caused by mutations in autism spectrum disorder (ASD) …
ensuing behavioral alterations caused by mutations in autism spectrum disorder (ASD) …
[HTML][HTML] Modern biomarkers for autism spectrum disorder: future directions
AR Jensen, AL Lane, BA Werner, SE McLees… - Molecular Diagnosis & …, 2022 - Springer
Autism spectrum disorder is an increasingly prevalent neurodevelopmental disorder in the
world today, with an estimated 2% of the population being affected in the USA. A major …
world today, with an estimated 2% of the population being affected in the USA. A major …
[HTML][HTML] Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with
unique changes in mitochondrial metabolism, including elevated respiration rates and …
unique changes in mitochondrial metabolism, including elevated respiration rates and …
[HTML][HTML] Increased maternal non-oxidative energy metabolism mediates association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and offspring …
S Thomson, K Drummond, M O'Hely… - Environment …, 2023 - Elsevier
Prenatal phthalate exposure has previously been linked to the development of autism
spectrum disorder (ASD). However, the underlying biological mechanisms remain unclear …
spectrum disorder (ASD). However, the underlying biological mechanisms remain unclear …
[HTML][HTML] Treatment of autism spectrum disorders by mitochondrial-targeted drug: Future of neurological diseases therapeutics
Autism is a neurodevelopmental disorder with a complex etiology that might involve
environmental and genetic variables. Recently, some epidemiological studies conducted in …
environmental and genetic variables. Recently, some epidemiological studies conducted in …
[HTML][HTML] Diet in treatment of autism spectrum disorders
Altering the diet to treat disease dates to c. 400 BC when starvation was used to reduce
seizures in persons with epilepsy. The current diversity of symptomology and mechanisms …
seizures in persons with epilepsy. The current diversity of symptomology and mechanisms …
Impacts of Gestational FireMaster 550 Exposure on the Neonatal Cortex Are Sex Specific and Largely Attributable to the Organophosphate Esters
SK Witchey, MG Doyle, JD Fredenburg… - …, 2023 - karger.com
Abstract Introduction: Flame retardants (FRs) are common bodily and environmental
pollutants, creating concern about their potential toxicity. We and others have found that the …
pollutants, creating concern about their potential toxicity. We and others have found that the …
[HTML][HTML] Ways to address perinatal mast cell activation and focal brain inflammation, including response to SARS-CoV-2, in autism spectrum disorder
TC Theoharides - Journal of Personalized Medicine, 2021 - mdpi.com
The prevalence of autism spectrum disorder (ASD) continues to increase, but no distinct
pathogenesis or effective treatment are known yet. The presence of many comorbidities …
pathogenesis or effective treatment are known yet. The presence of many comorbidities …
[HTML][HTML] Bioenergetic signatures of neurodevelopmental regression
Background: Studies have linked autism spectrum disorder (ASD) to physiological
abnormalities including mitochondrial dysfunction. Mitochondrial dysfunction may be linked …
abnormalities including mitochondrial dysfunction. Mitochondrial dysfunction may be linked …