Initial recognition of DNA damage is the crucial but poorly understood first step in DNA
repair by the human nucleotide excision repair (NER) and mismatch repair (MMR) systems …

Publisher Summary This chapter discusses the recent insights into how DNA sequence
affects DNA structure and how solvent-mediated alterations in DNA structure may play a role …

The width of the DNA minor groove varies with sequence and can be a major determinant of
DNA shape recognition by proteins. For example, the minor groove within the center of the …

The genome of the Lyme disease‐causing spirochete Borrelia burgdorferi encodes only a
single polypeptide from the integration host factor (IHF)/HU or 'DNABII'family of nucleoid …

The abundant Fis nucleoid protein selectively binds poorly related DNA sequences with
high affinities to regulate diverse DNA reactions. Fis binds DNA primarily through DNA …

Bacterial gene expression depends on the efficient functioning of global transcriptional
networks, however their interconnectivity and orchestration rely mainly on the action of …

The affinities of the bacteriophage 434 repressor for its various binding sites depend on the
type and/or concentration of monovalent cations. The ability of bacteriophage 434 repressor …

Two new bromine head-containing oxacalix [2] arene [2] triazines were designed and
synthesized. Owing to the bromine head and complementary V-shaped cavity, the solid state …

Abstract The Bacillus subtilis LexA protein represses the SOS response to DNA damage by
binding as a dimer to the consensus operator sequence 5′-CGAACN4GTTCG-3′. To …

Transcriptional pausing by human RNA polymerase II (RNAPII) in the HIV-1 LTR is caused
principally by a weak RNA: DNA hybrid that allows rearrangement of reactive or catalytic …