Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

After the virus has cleared—Can preclinical models be employed for Long COVID research?

EB Jansen, SN Orvold, CL Swan, A Yourkowski… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) can cause the life-
threatening acute respiratory disease called COVID-19 (Coronavirus Disease 2019) as well …

Animal models for SARS‐CoV‐2 infection and pathology

Z Bi, W Hong, J Yang, S Lu, X Peng - MedComm, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the etiology of
coronavirus disease 2019 (COVID‐19) pandemic. Current variants including Alpha, Beta …

Comparative Pathogenesis of Severe Acute Respiratory Syndrome Coronaviruses

J Zhang, M Rissmann, T Kuiken… - Annual Review of …, 2024 - annualreviews.org
Over the last two decades the world has witnessed the global spread of two genetically
related highly pathogenic coronaviruses, severe acute respiratory syndrome coronavirus …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) dose, infection, and disease outcomes for coronavirus disease 2019 (COVID-19): a review

LM Brosseau, K Escandón, AK Ulrich… - Clinical Infectious …, 2022 - academic.oup.com
The relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
dose, infection, and coronavirus disease 2019 (COVID-19) outcomes remains poorly …

Infectious droplet exposure is an inefficient route for SARS-CoV-2 infection in the ferret model

J James, AMP Byrne, H Goharriz… - Journal of General …, 2022 - microbiologyresearch.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19) in humans, has a wide host range, naturally infecting …

Key considerations to improve the normalization, interpretation and reproducibility of morbidity data in mammalian models of viral disease

JA Belser, TJ Kieran, ZA Mitchell… - Disease Models & …, 2024 - journals.biologists.com
Viral pathogenesis and therapeutic screening studies that utilize small mammalian models
rely on the accurate quantification and interpretation of morbidity measurements, such as …

Sex differences in the cardiac stress response following SARS-CoV-2 infection of ferrets

S Rouhana, K Jacyniak, ME Francis… - American Journal …, 2023 - journals.physiology.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection damages the
heart, increasing the risk of adverse cardiovascular events. Female sex protects against …

SARS-CoV-2 Aerosol and Intranasal Exposure Models in Ferrets

EE Zumbrun, SE Zak, ED Lee, PA Bowling, SI Ruiz… - Viruses, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the worldwide COVID-19 pandemic. Animal models are extremely helpful for testing …

[HTML][HTML] The X-quisite X-ception: Sex Differences with Immune Responses

KS Forsyth, N Jiwrajka, CD Lovell… - Nature reviews …, 2024 - ncbi.nlm.nih.gov
There are significant sex-based differences in immune responses to pathogens and self-
antigens, with human females exhibiting increased susceptibility to various autoimmune …