Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Cells must duplicate their mass in order to proliferate. Glucose and glutamine are the major
nutrients consumed by proliferating mammalian cells, but the extent to which these and …

To understand complex biological systems requires the integration of experimental and
computational research—in other words a systems biology approach. Computational …

The crucial role of lipids in cell, tissue and organ physiology is demonstrated by a large
number of genetic studies and by many human diseases that involve the disruption of lipid …

Many metabolomics, and other high-content or high-throughput, experiments are set up
such that the primary aim is the discovery of biomarker metabolites that can discriminate …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and rational drug design, the number of successful single-target drugs did not …

Nutrigenomics is the application of high-throughput genomics tools in nutrition research.
Applied wisely, it will promote an increased understanding of how nutrition influences …

Aerobic glycolysis or the Warburg Effect (WE) is characterized by the increased metabolism
of glucose to lactate. It remains unknown what quantitative changes to the activity of …

Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …