Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …

The hippocampus receives its major cortical input from the medial entorhinal cortex (MEC)
and the lateral entorhinal cortex (LEC). It is commonly believed that the MEC provides …

The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

Animals can navigate vast distances and often display behaviours or activities that indicate a
detailed, internal spatial representation of their surrounding environment or a 'cognitive …

Rats and mice have been demonstrated to show episodic-like memory, a prototype of
episodic memory, as defined by an integrated memory of the experience of an object or …

In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the
entorhinal cortex with a focus on the concept of parallel cortical connectivity streams. The …

Whether or how the pathogenic disruptions in endosomal trafficking observed in Alzheimer's
disease (AD) are linked to its anatomical vulnerability remain unknown. Here, we began …

The subregions of the entorhinal cortex (EC) are conventionally thought to compute
dichotomous representations for spatial processing, with the medial EC (MEC) providing a …

The current model of the organization of the medial temporal lobe (MTL) episodic memory
system assumes that two functionally different" where" and" what" pathways enter MTL as …

The Akt family of kinases exerts many of its cellular effects via the activation of the
mammalian target of rapamycin (mTOR) kinase through a series of intermediary proteins …