Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

In the recent years, the prevalence of HPV-positive oropharyngeal squamous cell carcinoma
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …

Receptor tyrosine kinases (RTKs) are cell surface receptors that bind growth factor ligands
and initiate cellular signaling. Of the 20 classes of RTKs, 7 classes, IV, VIII, and X, are linked …

Management of metastatic head and neck squamous cell carcinoma is evolving as new
systemic therapies have led to improvements in survival, and as advances in locoregional …

Mucosal melanoma (MM), an aggressive rare subtype of melanoma, is distinct from
cutaneous melanoma and has poor prognoses. We addressed the lack of cell models for …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type,
has often an aggressive course and is poorly responsive to current therapeutic approaches …

Head and neck cancer (HNC) is a term collectively used to describe a heterogeneous group
of tumors that arise in the oral cavity, larynx, nasopharynx, oropharynx, and hypopharynx …

Simple Summary In recent years, checkpoint inhibitor treatment of tumors has caused a stir.
The response of patients with metastases showed outstanding success for some cancer …

Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of many cancer
types, including head and neck cancers (HNC). When checkpoint and partner proteins bind …

Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …