Beyond ligand binding: Single molecule observation reveals how riboswitches integrate multiple signals to balance bacterial gene regulation

A Chauvier, NG Walter - Current Opinion in Structural Biology, 2024 - Elsevier
Riboswitches are specialized RNA structures that orchestrate gene expression in response
to sensing specific metabolite or ion ligands, mostly in bacteria. Upon ligand binding, these …

Tracking transcription–translation coupling in real time

NS Qureshi, O Duss - Nature, 2024 - nature.com
A central question in biology is how macromolecular machines function cooperatively. In
bacteria, transcription and translation occur in the same cellular compartment, and can be …

Co-transcriptional RNA processing boosts zygotic gene activation

J Xu, X Li, X Hao, X Hu, S Ma, Y Hong, J Zhang, D Yan… - bioRxiv, 2024 - biorxiv.org
Transcription decodes protein-coding genes and interprets regulatory information
embedded in the genome by generating RNA. In eukaryotes, gene transcription is coupled …