Rectal cancer treatment has evolved during the past 40 years with the use of a standardized
surgical technique for tumour resection: total mesorectal excision. A dramatic reduction in …

Colorectal cancer (CRC) is one of the most prevalent and deadly cancers worldwide.
Despite recent improvements in treatment and prevention, most of the current therapeutic …

The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring high-
quality patient care by advancing the science, prevention, and management of disorders …

Importance Novel sensitive methods for detection and monitoring of residual disease can
improve postoperative risk stratification with implications for patient selection for adjuvant …

Background Organ preservation after reaching clinical complete response on neoadjuvant
therapy is gaining interest for rectal cancers, although the role of radiation dose escalation is …

Background Watch and wait is a novel management strategy in patients with rectal cancer
who have a clinical complete response after neoadjuvant chemoradiotherapy. Surveillance …

Background & Aims In accordance with guidelines, most patients with T1 colorectal cancers
(CRC) undergo surgical resection with lymph node dissection, despite the low incidence (∼ …

Importance Management of colorectal cancer (CRC) has been updated continuously over
the past 2 decades. While the combination of these initiatives has had implications for …

Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal
cancer. Adjuvant chemotherapy is usually used for distant control. However, not all patients …

Magnetic resonance imaging (MRI) has gained increasing importance in the management of
rectal cancer over the last two decades. The role of MRI in patients with rectal cancer has …