Obesity and diabetes have both been associated with an increased risk of cancer. In the
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …

Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Background Epidemiological studies have reported conflicting findings on the potential
adverse effects of long-term antihypertensive medication use on cancer risk. Naturally …

Background Breast cancer (BC) has the highest cancer incidence and mortality in women
worldwide. Observational epidemiological studies suggest a positive association between …

Importance Preclinical and epidemiological studies indicate a potential chemopreventive
role of statins in epithelial ovarian cancer risk. Objective To evaluate the association of …

Background Previous studies had limited power to assess the associations of circulating
insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) with clinically relevant …

Previous studies had limited power to assess the associations of testosterone with
aggressive disease as a primary endpoint. Further, the association of genetically predicted …

Estimated genetic associations with prognosis, or conditional on a phenotype (eg disease
incidence), may be affected by collider bias, whereby conditioning on the phenotype …

Autoimmune diseases (ADs) are a broad range of disorders which are characterized by long-
term inflammation and tissue damage arising from an immune response against one's own …

The involvement of cardiovascular disease in cancer onset and development represents a
contemporary interest in basic science. It has been recognized, from the most recent …