[HTML][HTML] Large and small platelets—(When) do they differ?

S Handtke, T Thiele - Journal of Thrombosis and Haemostasis, 2020 - Elsevier
Platelets are most important in providing cellular hemostasis but also take part in
inflammation and immune processes. Increased platelet size has been regarded as a …

Reticulated platelets: analytical aspects and clinical utility

JJML Hoffmann - Clinical Chemistry and Laboratory Medicine (CCLM …, 2014 - degruyter.com
Reticulated platelets are immature platelets circulating in blood; they reflect the activity of
megakaryopoiesis in the bone marrow. Therefore, they can be used as a non-invasive test in …

Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to …

R Marcucci, AM Gori, R Paniccia, B Giusti, S Valente… - Circulation, 2009 - Am Heart Assoc
Background—The clinical impact of platelet aggregation assessed by point-of-care assays is
unknown. We sought to evaluate whether high residual platelet reactivity (RPR) to ADP …

Association of immature platelets with adverse cardiovascular outcomes

H Ibrahim, RC Schutt, B Hannawi, T DeLao… - Journal of the American …, 2014 - jacc.org
Background: Immature platelets are less responsive to the effects of antiplatelet drugs and
contain messenger ribonucleic acid that is translationally active. They can be measured …

Immature platelets in patients with acute coronary syndromes

EL Grove, AM Hvas… - Thrombosis and …, 2009 - thieme-connect.com
Platelets newly released from the bone marrow are RNA-containing and more
haemostatically active than mature platelets. Immature platelets are reliably quantified by …

The causal role of megakaryocyte–platelet hyperactivity in acute coronary syndromes

JF Martin, SD Kristensen, A Mathur, EL Grove… - Nature Reviews …, 2012 - nature.com
Platelets are causally involved in coronary artery obstruction in acute coronary syndromes
(ACS). This cell type is unique to mammals and its production, which is unlike that of any …

Reticulated platelets predict cardiovascular death in acute coronary syndrome patients

F Cesari, R Marcucci, AM Gori… - Thrombosis and …, 2013 - thieme-connect.com
Reticulated platelets (RP) are newly-formed platelets with a greater mass, a residual amount
of RNA and an increased prothrombotic potential. No studies investigating the association …

[HTML][HTML] Resveratrol, at Concentrations Attainable with Moderate Wine Consumption, Stimulates Human Platelet Nitric Oxide Production3

P Gresele, P Pignatelli, G Guglielmini, R Carnevale… - The Journal of …, 2008 - Elsevier
The mechanisms through which moderate wine consumption reduces ischemic
cardiovascular events are not yet fully unraveled. Grape extracts or a mixture of the …

[HTML][HTML] Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease

EL Grove, AM Hvas, SB Mortensen, SB Larsen… - Journal of Thrombosis …, 2011 - Elsevier
Background: Previous studies have demonstrated considerable variation in the antiplatelet
effect of aspirin. Objectives: To investigate the impact of platelet turnover on the antiplatelet …

Prognostic effect of mean platelet volume in patients with coronary artery disease

N Sansanayudh, P Numthavaj… - Thrombosis and …, 2015 - thieme-connect.com
Large platelets with high haemostatic activity may lead to increased platelet aggregation..
Mean platelet volume (MPV), an indicator of platelet reactivity, may emerge as a prognostic …