Chiral metal-organic frameworks and their composites as stationary phases for liquid chromatography chiral separation: a minireview
C Liu, K Quan, J Chen, X Shi, H Qiu - Journal of Chromatography A, 2023 - Elsevier
Chiral metal organic frameworks (CMOFs) are a kind of crystal porous framework material
that has attracted increasing attention due to the customizable combination of metal nodes …
that has attracted increasing attention due to the customizable combination of metal nodes …
One reaction–double stereoinduction: C–H activation as a privileged route towards complex atropisomeric molecules
A Luc, J Wencel-Delord - Chemical Communications, 2023 - pubs.rsc.org
Expanding the importance of chirality and implementation of stereogenic information within
complex molecular design has recently reached a new level: design of innovative …
complex molecular design has recently reached a new level: design of innovative …
Multifaceted view on the mechanism of a photochemical deracemization reaction
RJ Kutta, J Großkopf, N van Staalduinen… - Journal of the …, 2023 - ACS Publications
Upon irradiation in the presence of a chiral benzophenone catalyst (5 mol%), a racemic
mixture of a given chiral imidazolidine-2, 4-dione (hydantoin) can be converted almost …
mixture of a given chiral imidazolidine-2, 4-dione (hydantoin) can be converted almost …
Double cobalt-catalyzed atroposelective C–H activation: One-step synthesis of atropisomeric indoles bearing vicinal C–C and C–N diaxes
Expanding the borders of asymmetric synthesis by designing original chiral molecules and
sustainable strategies to synthesize them holds great promise not only for the …
sustainable strategies to synthesize them holds great promise not only for the …
Phytochemicals involved in mitigating silent toxicity induced by heavy metals
J Ceramella, AC De Maio, G Basile, A Facente, E Scali… - Foods, 2024 - mdpi.com
Heavy metals (HMs) are natural elements present in the Earth's crust, characterised by a
high atomic mass and a density more than five times higher than water. Despite their origin …
high atomic mass and a density more than five times higher than water. Despite their origin …
Chirality of new drug approvals (2013–2022): trends and perspectives
RU McVicker, NM O'Boyle - Journal of Medicinal Chemistry, 2024 - ACS Publications
Many drugs are chiral with their chirality determining their biological interactions, safety, and
efficacy. Since the 1980s, there has been a regulatory preference to bring single enantiomer …
efficacy. Since the 1980s, there has been a regulatory preference to bring single enantiomer …
Impact of cytochrome P450 enzymes on the phase I metabolism of drugs
D Iacopetta, J Ceramella, A Catalano, E Scali… - Applied Sciences, 2023 - mdpi.com
The cytochrome P450 (CYP) enzyme family is the major enzyme system catalyzing the
phase I metabolism of xenobiotics, including pharmaceuticals and toxic compounds in the …
phase I metabolism of xenobiotics, including pharmaceuticals and toxic compounds in the …
Microwave Three-Wave Mixing Spectroscopy of Chiral Molecules in Weakly Bound Complexes
W Sun, M Schnell - The Journal of Physical Chemistry Letters, 2023 - ACS Publications
Since the first experimental implementation in 2013, microwave three-wave mixing has
emerged as a robust spectroscopic approach for analyzing and controlling chiral molecules …
emerged as a robust spectroscopic approach for analyzing and controlling chiral molecules …
Postsynthetic Modification Strategy for Constructing Electrochemiluminescence-Active Chiral Covalent Organic Frameworks Performing Efficient Enantioselective …
L Tan, W Cai, F Wang, J Li, D Wu, Y Kong - Analytical Chemistry, 2024 - ACS Publications
Electrochemiluminescence (ECL), integrating the characteristics of electrochemistry and
fluorescence, has the advantages of high sensitivity and low background. However, only a …
fluorescence, has the advantages of high sensitivity and low background. However, only a …
Negative Nonlinear CD–ee Dependence in Polycrystalline BINOL Thin Films
K Liang, F Ristow, K Li, J Pittrich, N Fehn… - Journal of the …, 2023 - ACS Publications
Generally, the relationship between the observed circular dichroism and the enantiomeric
excess in chiral systems (CD–ee dependence) is linear. While positive nonlinear behavior …
excess in chiral systems (CD–ee dependence) is linear. While positive nonlinear behavior …