To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …

Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Background At interim analysis in a phase 3, observer-blinded, placebo-controlled clinical
trial, the mRNA-1273 vaccine showed 94.1% efficacy in preventing coronavirus disease …

Background The safety, reactogenicity, immunogenicity, and efficacy of the mRNA-1273
coronavirus disease 2019 (Covid-19) vaccine in young children are unknown. Methods Part …

Background The efficacy of SARS-CoV-2 vaccines in preventing severe COVID-19 illness
and death is uncertain due to the rarity of data in individual trials. How well the antibody …

Background Vaccination of children to prevent coronavirus disease 2019 (Covid-19) is an
urgent public health need. The safety, immunogenicity, and efficacy of the mRNA-1273 …

The COVID-19 pandemic and its associated vaccine have highlighted vaccine hesitancy
among healthcare workers (HCWs). Vaccine hesitancy among this group existed prior to the …

Since the first successful application of messenger ribonucleic acid (mRNA) as a vaccine
agent in a preclinical study nearly 30 years ago, numerous advances have been made in …

Objective To evaluate the effectiveness of heterologous and homologous covid-19 vaccine
regimens with and without boosting in preventing covid-19 related infection, hospital …

Background The temporal evolution of SARS-CoV-2 vaccine efficacy and effectiveness (VE)
against infection, symptomatic, and severe COVID-19 is incompletely defined. The temporal …