Sizing up the bacterial cell cycle
L Willis, KC Huang - Nature Reviews Microbiology, 2017 - nature.com
It is remarkable how robustly a bacterial species can maintain its preferred size. This
capacity is intimately related to control of the cell cycle: cell size and growth rate determine …
capacity is intimately related to control of the cell cycle: cell size and growth rate determine …
Modeling cell size regulation: From single-cell-level statistics to molecular mechanisms and population-level effects
Most microorganisms regulate their cell size. In this article, we review some of the
mathematical formulations of the problem of cell size regulation. We focus on coarse …
mathematical formulations of the problem of cell size regulation. We focus on coarse …
[图书][B] Stochastic processes in cell biology
PC Bressloff - 2014 - Springer
One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …
components of a living cell operate in a highly noisy environment. What are the specific …
Homeostasis of protein and mRNA concentrations in growing cells
J Lin, A Amir - Nature communications, 2018 - nature.com
Many experiments show that the numbers of mRNA and protein are proportional to the cell
volume in growing cells. However, models of stochastic gene expression often assume …
volume in growing cells. However, models of stochastic gene expression often assume …
Direct single-cell observation of a key Escherichia coli cell-cycle oscillator
I Iuliani, G Mbemba, MC Lagomarsino, B Sclavi - Science Advances, 2024 - science.org
Initiation of DNA replication in Escherichia coli is coupled to cell size via the DnaA protein,
whose activity is dependent on its nucleotide-bound state. However, the oscillations in DnaA …
whose activity is dependent on its nucleotide-bound state. However, the oscillations in DnaA …
Individuality and slow dynamics in bacterial growth homeostasis
Microbial growth and division are fundamental processes relevant to many areas of life
science. Of particular interest are homeostasis mechanisms, which buffer growth and …
science. Of particular interest are homeostasis mechanisms, which buffer growth and …
Bacterial cell-size changes resulting from altering the relative expression of Min proteins
The timing of cell division, and thus cell size in bacteria, is determined in part by the
accumulation dynamics of the protein FtsZ, which forms the septal ring. FtsZ localization …
accumulation dynamics of the protein FtsZ, which forms the septal ring. FtsZ localization …
Statistical mechanics for metabolic networks during steady state growth
D De Martino, A Mc Andersson, T Bergmiller… - Nature …, 2018 - nature.com
Which properties of metabolic networks can be derived solely from stoichiometry? Predictive
results have been obtained by flux balance analysis (FBA), by postulating that cells set …
results have been obtained by flux balance analysis (FBA), by postulating that cells set …
Universality of phenotypic distributions in bacteria
Some phenotypic properties in bacteria exhibit universal statistics, with distributions
collapsing under scaling. The extent and origins of such universality are not well …
collapsing under scaling. The extent and origins of such universality are not well …
Protein concentration fluctuations in the high expression regime: Taylor's law and its mechanistic origin
Protein concentration in a living cell fluctuates over time due to noise in growth and division
processes. In the high expression regime, variance of the protein concentration in a cell is …
processes. In the high expression regime, variance of the protein concentration in a cell is …