Protozoan parasites have developed elaborate motility systems that facilitate infection and
dissemination. For example, amoebae use actin-rich membrane extensions called …

Regulating the number of progeny generated by replicative cell cycles is critical for any
organism to best adapt to its environment. Classically, the decision whether to divide further …

Malaria is caused by unicellular Plasmodium parasites. Plasmodium relies on diverse
microtubule cytoskeletal structures for its reproduction, multiplication, and dissemination …

For its replication within red blood cells, the malaria parasite depends on a highly active and
regulated lipid metabolism. Enzymes involved in lipid metabolic processes such as …

Malaria is transmitted when an infected Anopheles mosquito deposits Plasmodium
sporozoites in the skin during a bite. Sporozoites are formed within oocysts at the mosquito …

Leishmania species, members of the kinetoplastid parasites, cause leishmaniasis, a
neglected tropical disease, in millions of people worldwide. Leishmania has a complex life …

To best understand parasite, host, and vector morphologies, host–parasite interactions, and
to develop new drug and vaccine targets, structural data should, ideally, be obtained and …

Plasmodium parasites, the causative agents of malaria, display a well-regulated lipid
metabolism required to ensure their survival in the human host as well as in the mosquito …

Babesiosis is considered an emerging disease because its incidence has significantly
increased in the last 30 years, providing evidence of the expanding range of this rare but …

Plasmodium parasites rely on a functional electron transport chain (ETC) within their
mitochondrion for proliferation, and compounds targeting mitochondrial functions are …