The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies

S Elad, N Yarom, Y Zadik… - CA: a cancer journal …, 2022 - Wiley Online Library
Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that
affects patients' function, quality of life, and ability to tolerate treatment. In certain patients …

Radiation oncology in the era of precision medicine

M Baumann, M Krause, J Overgaard, J Debus… - Nature Reviews …, 2016 - nature.com
Technological advances and clinical research over the past few decades have given
radiation oncologists the capability to personalize treatments for accurate delivery of …

[HTML][HTML] COVID-19: Global radiation oncology's targeted response for pandemic preparedness

R Simcock, TV Thomas, C Estes, AR Filippi… - Clinical and translational …, 2020 - Elsevier
As the global COVID-19 pandemic escalates there is a need within radiation oncology to
work to support our patients in the best way possible. Measures are required to reduce …

Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522

KK Ang, Q Zhang, DI Rosenthal… - Journal of clinical …, 2014 - ascopubs.org
Purpose Combining cisplatin or cetuximab with radiation improves overall survival (OS) of
patients with stage III or IV head and neck carcinoma (HNC). Cetuximab plus platinum …

Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

B Lacas, J Bourhis, J Overgaard, Q Zhang… - The Lancet …, 2017 - thelancet.com
Summary Background The Meta-Analysis of Radiotherapy in squamous cell Carcinomas of
Head and neck (MARCH) showed that altered fractionation radiotherapy is associated with …

Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma

RL Ferris, W Westra - Annual Review of Pathology: Mechanisms …, 2023 - annualreviews.org
Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV-OPSCC)
has one of the most rapidly increasing incidences of any cancer in high-income countries …

The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities

C WalshJoseph, C KolbHartmuth - Antioxidants & redox signaling, 2014 - liebertpub.com
Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms

M Cojoc, K Mäbert, MH Muders, A Dubrovska - Seminars in cancer biology, 2015 - Elsevier
Similar to normal tissue, many tumors have a hierarchical organization where tumorigenic
cancer stem cells (CSCs) differentiate into non-tumorigenic progenies. A host of studies …

[HTML][HTML] Radiation therapy in head and neck cancer

AF Alfouzan - Saudi medical journal, 2021 - ncbi.nlm.nih.gov
This review summarizes the beginning of radiotherapy, techniques of modern radiation
therapy with different types, toxicities induced by radiotherapy and their management. Head …

[HTML][HTML] Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer

AA Forastiere, H Goepfert, M Maor… - … England Journal of …, 2003 - Mass Medical Soc
Background Induction chemotherapy with cisplatin plus fluorouracil followed by radiotherapy
is the standard alternative to total laryngectomy for patients with locally advanced laryngeal …