In this Review, we describe the singular success of attractor neural network models in
describing how the brain maintains persistent activity states for working memory, corrects …

Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

The large number of ion channels found in all nervous systems poses fundamental
questions concerning how the characteristic intrinsic properties of single neurons are …

Timing is critical to most forms of learning, behavior, and sensory-motor processing.
Converging evidence supports the notion that, precisely because of its importance across a …

All nervous systems are subject to neuromodulation. Neuromodulators can be delivered as
local hormones, as cotransmitters in projection neurons, and through the general circulation …

Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

Central oscillators are primordial neural circuits that generate and control rhythmic
movements,. Mechanistic understanding of these circuits requires genetic identification of …

Theoretical neuroscience provides a quantitative basis for describing what nervous systems
do, determining how they function, and uncovering the general principles by which they …

Recent advances in integrative studies of locomotion have revealed several general
principles. Energy storage and exchange mechanisms discovered in walking and running …

Attention has been found to have a wide variety of effects on the responses of neurons in
visual cortex. We describe a model of attention that exhibits each of these different forms of …