Extrapineal melatonin: sources, regulation, and potential functions

D Acuña-Castroviejo, G Escames, C Venegas… - Cellular and molecular …, 2014 - Springer
Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is
considered an indoleamine from a biochemical point of view because the melatonin …

[HTML][HTML] Development of the circadian system in early life: maternal and environmental factors

SD Wong, KP Wright Jr, RL Spencer, C Vetter… - Journal of physiological …, 2022 - Springer
In humans, an adaptable internal biological system generates circadian rhythms that
maintain synchronicity of behavior and physiology with the changing demands of the 24-h …

Development of fetal and neonatal sleep and circadian rhythms

M Mirmiran, YGH Maas, RL Ariagno - Sleep medicine reviews, 2003 - Elsevier
The origin of sleep and circadian rhythms development is found during the fetal period. Both
quiet (NREM) and active (REM) sleep are distinguishable during the last 10 weeks of …

Changes of serum melatonin level and its relationship to feto‐placental unit during pregnancy

Y Nakamura, H Tamura, S Kashida… - Journal of pineal …, 2001 - Wiley Online Library
Serum melatonin concentrations were studied in normal pregnant women and in women
with several types of pathologic pregnancies, eg, twins, preeclampsia or intrauterine growth …

Nocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases

MH Smolensky, LL Sackett-Lundeen… - Chronobiology …, 2015 - Taylor & Francis
Routine exposure to artificial light at night (ALAN) in work, home, and community settings is
linked with increased risk of breast and prostate cancer (BC, PC) in normally sighted women …

Maternal‐fetal transfer of melatonin in pregnant women near term

Y Okatani, K Okamoto, K Hayashi… - Journal of pineal …, 1998 - Wiley Online Library
Our objective was to evaluate the maternal‐fetal transfer of melatonin in pregnant women.
Serum melatonin concentration was measured by high‐performance liquid chromatography …

Melatonin

RC ZIMMERMANN, JM OLCESE - Treatment of the Postmenopausal …, 2007 - Elsevier
Publisher Summary Molecular biology has dispersed some of the myths surrounding
melatonin. Melatonin production sites can be clearly identified by detecting message and …

Sleep-wake states and their regulatory mechanisms throughout early human development

P Peirano, C Algarı́n, R Uauy - The Journal of pediatrics, 2003 - Elsevier
The emergence of sleep states is one of the most significant aspects of development.
Descriptions of both neonatal and late fetal behavior and studies on the organization of …

Melatonin increases activities of glutathione peroxidase and superoxide dismutase in fetal rat brain

Y Okatani, A Wakatsuki, C Kaneda - Journal of pineal research, 2000 - Wiley Online Library
Melatonin is a powerful scavenger of oxygen free radicals. In humans, melatonin is rapidly
transferred from the maternal to the fetal circulation. To investigate whether or not maternal …

Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: two years' experience

A Molina‐Carballo, A Muñoz‐Hoyos… - Journal of pineal …, 1997 - Wiley Online Library
Molina‐Carballo A, Muñoz‐Hoyos A, Reiter RJ, Sánchez‐Forte M, Moreno‐Madrid F, Rufo‐
Campos M, Molina‐Font JA, Acuña‐Castroviejo D. Utility of high doses of melatonin as …