The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

Parallel contributions of cerebellar, striatal and M1 mechanisms to motor sequence learning

VB Penhune, CJ Steele - Behavioural brain research, 2012 - Elsevier
When learning a new motor sequence, we must execute the correct order of movements
while simultaneously optimizing sensorimotor parameters such as trajectory, timing, velocity …

Trisomy 21 and early brain development

TF Haydar, RH Reeves - Trends in neurosciences, 2012 - cell.com
Trisomy for human chromosome 21 (Hsa21) results in Down syndrome (DS). The finished
human genome sequence provides a thorough catalog of the genetic elements whose …

A New Projection From the Deep Cerebellar Nuclei to the Hippocampus via the Ventrolateral and Laterodorsal Thalamus in Mice

P Bohne, MK Schwarz, S Herlitze… - Frontiers in neural circuits, 2019 - frontiersin.org
The cerebellar involvement in cognitive functions such as attention, language, working
memory, emotion, goal-directed behavior and spatial navigation is constantly growing …

Cerebellum shapes hippocampal spatial code

C Rochefort, A Arabo, M André, B Poucet, E Save… - Science, 2011 - science.org
Spatial representation is an active process that requires complex multimodal integration
from a large interacting network of cortical and subcortical structures. We sought to …

Back to front: cerebellar connections and interactions with the prefrontal cortex

TC Watson, N Becker, R Apps… - Frontiers in systems …, 2014 - frontiersin.org
Although recent neuroanatomical evidence has demonstrated closed-loop connectivity
between prefrontal cortex and the cerebellum, the physiology of cerebello-cerebral circuits …

Interaction between hippocampus and cerebellum crus I in sequence-based but not place-based navigation

K Iglói, CF Doeller, AL Paradis, K Benchenane… - Cerebral …, 2015 - academic.oup.com
To examine the cerebellar contribution to human spatial navigation we used functional
magnetic resonance imaging and virtual reality. Our findings show that the sensory-motor …

A liaison brought to light: cerebellum-hippocampus, partners for spatial cognition

L Rondi-Reig, AL Paradis, M Fallahnezhad - The Cerebellum, 2022 - Springer
This review focuses on the functional and anatomical links between the cerebellum and the
hippocampus and the role of their interplay in goal-directed navigation and spatial cognition …

The cerebellum: a new key structure in the navigation system

C Rochefort, JM Lefort, L Rondi-Reig - Frontiers in neural circuits, 2013 - frontiersin.org
Early investigations of cerebellar function focused on motor learning, in particular on
eyeblink conditioning and adaptation of the vestibulo-ocular reflex, and led to the general …

Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model

I Das, JM Park, JH Shin, SK Jeon, H Lorenzi… - Science translational …, 2013 - science.org
Down syndrome (DS) is among the most frequent genetic causes of intellectual disability,
and ameliorating this deficit is a major goal in support of people with trisomy 21. The Ts65Dn …