Intracerebral hemorrhage (ICH) is the second most common subtype of stroke and a critical
disease usually leading to severe disability or death. ICH is more common in Asians …

Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders
with different pathological backgrounds. The advanced vasculature net of cerebral vessels …

Two decades of epidemiological research shows that silent cerebrovascular disease is
common and is associated with future risk for stroke and dementia. It is the most common …

Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Amyloid imaging related abnormalities (ARIA) have now been reported in clinical trials with
multiple therapeutic avenues to lower amyloid-β burden in Alzheimer's disease (AD). In …

Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in
individuals with cerebrovascular disease and dementia, and in normal ageing. There has …

Objective: Brain microbleeds on gradient-recalled echo (GRE) T2*-weighted MRI may be a
useful biomarker for bleeding-prone small vessel diseases, with potential relevance for …

Sporadic cerebral amyloid angiopathy (CAA) is a common age related cerebral small vessel
disease, characterised by progressive deposition of amyloid-β (Aβ) in the wall of small to …

We examined if baseline levels of cognitive reserve (CR) and of Alzheimer's disease (AD)
biomarkers modify the rate of change in cognition among individuals with normal cognition …