Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, there have been
a few variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of …

The SARS-CoV-2 Omicron (B. 1.1529) variant was designated as a variant of concern (VOC)
by the World Health Organization (WHO) on November 26, 2021. Within two months, it had …

Background The ZF2001 vaccine, which contains a dimeric form of the receptor-binding
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …

Omicron SARS-CoV-2 is rapidly spreading worldwide. To delineate the impact of emerging
mutations on spike's properties, we performed systematic structural analyses on apo …

Breakthrough infections by SARS-CoV-2 variants become the global challenge for
pandemic control. Previously, we developed the protein subunit vaccine ZF2001 based on …

SARS-CoV-2 neutralizing antibodies play a critical role in COVID-19 prevention and
treatment but are challenged by viral evolution and the emergence of novel escape variants …

SARS-CoV-2 Omicron variant has presented significant challenges to current antibodies
and vaccines. Herein, we systematically compared the efficacy of 50 human monoclonal …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had
become a global concern because of its unexpectedly high pathogenicity and …

The Omicron variant rapidly became the dominant SARS‐CoV‐2 strain in South Africa and
elsewhere. This review explores whether this rise was due to an increased transmission of …

With the widespread vaccinations against coronavirus disease 2019 (COVID-19), we are
witnessing gradually waning neutralizing antibodies and increasing cases of breakthrough …