Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Background Excessive exposure of the skin to UV radiation (UVR) triggers a remodeling of
the immune system and leads to the photoaging state which is reminiscent of chronological …

Aging induces a series of immune related changes, which is called immunosenescence,
playing important roles in many age-related diseases, especially neurodegenerative …

Post-translational modifications (PTMs) have been proposed as a link between the oxidative
stress-inflammation-ageing trinity, thereby affecting several hallmarks of ageing …

Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

The senescence‐associated secretory phenotype (SASP), where senescent cells produce a
variety of secreted proteins including inflammatory cytokines, chemokines, matrix …

Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …

Sarcopenia, a geriatric syndrome that is characterized by a progressive and generalized
skeletal muscle disorder, can be associated with many comorbidities, including obesity …

Oxidative stress (OS) is primarily caused by the formation of free radicals and reactive
oxygen species; it is considered as one of the prominent factors in slowing down and …

The function of the immune system declines during aging, compromising its response
against pathogens, a phenomenon termed as “immunosenescence.” Alterations of the …